Combined treatment with vitamin B 12b and ascorbic acid causes in vitro DNA degradation in tumor cells

Bulletin of Experimental Biology and Medicine

Volumn 131, Issue 4, 2001, Pages 364-366

  Medvedev, A I ^a   Akatov, V S ^a   Kreshchenko, N D ^a   Solov'eva, M E ^a   Leshchenko, V V ^a   Lezhnev, E I ^a   Yakubovskaya, R I ^a,b  

^a INSTITUTE OF THEORETICAL AND EXPERIMENTAL BIOPHYSICS   (Russian Federation)

^b INSTITUTE OF BIOMEDICAL CHEMISTRY   (Russian Federation)

Author keywords

Ascorbic acid; DNA degradation; Hydroxycobalamin; Tumor cells; Vitamin B 12b

Indexed keywords

ASCORBIC ACID; DNA FRAGMENT; DOUBLE STRANDED DNA; HYDROXOCOBALAMIN;

ANIMAL CELL; ARTICLE; CELL SUSPENSION; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DNA DEGRADATION; DOSE RESPONSE; DRUG EFFECT; EHRLICH ASCITES TUMOR CELL; GAMMA IRRADIATION; GENOTOXICITY; HEP 2 CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; INCUBATION TIME; LARYNX CARCINOMA; MOUSE; NONHUMAN; RADIATION DOSE; TEMPERATURE; TUMOR CELL CULTURE;

ASCORBIC ACID; DEOXYRIBONUCLEASES; DNA DAMAGE; DNA, NEOPLASM; DRUG SYNERGISM; HUMANS; HYDROXOCOBALAMIN; TUMOR CELLS, CULTURED;

EID: 0035212710     PISSN: 00074888     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1017960404705     Document Type: Article

References (9)