Development of a stereoselective practical synthetic route to indolmycin, a candidate anti-H. pylori agent

Chemical and Pharmaceutical Bulletin

Volumn 49, Issue 12, 2001, Pages 1604-1608

  Hasuoka, Atsushi ^a   Nakayama, Yutaka ^a   Adachi, Mari ^a   Kamiguchi, Hidenori ^b   Kamiyama, Keiji ^a  

^a Medicinal Chemistry Research Laboratories II   (Japan)

^b TAKEDA PHARMACEUTICAL COMPANY LIMITED   (Japan)

Author keywords

Amine exchange; Diastereoselective synthesis; Guanidine; Indolmycin; Metabolite

Indexed keywords

AMINE; ANTIINFECTIVE AGENT; DICHLOROMETHANE; ESTER DERIVATIVE; GUANIDINE; HYDROXYACID; INDOLMYCIN; METHYLAMINE; OXAZOLONE; POTASSIUM DERIVATIVE; TERT BUTYL ALCOHOL; UNCLASSIFIED DRUG;

ARTICLE; CRYSTALLIZATION; DRUG DETERMINATION; DRUG STRUCTURE; DRUG SYNTHESIS; HELICOBACTER PYLORI; NONHUMAN; OPTICAL ROTATION; RAT; REACTION ANALYSIS; STEREOCHEMISTRY;

AMINES; ANIMALS; ANTI-BACTERIAL AGENTS; BIOTRANSFORMATION; HELICOBACTER PYLORI; INDICATORS AND REAGENTS; INDOLES; MAGNETIC RESONANCE SPECTROSCOPY; RATS; STEREOISOMERISM;

EID: 0035212685     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.49.1604     Document Type: Article

References (19)