Determination of ototoxicity of common otic drops using isolated cochlear outer hair cells

Laryngoscope

Volumn 111, Issue 12, 2001, Pages 2105-2108

  Jinn, Tae Hoon ^a   Kim, Paul D ^a   Russell, Paul T ^a   Church, Christopher A ^a   John, Earnest O ^a   Jung, Timothy T K ^a,b  

^a LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NONE   (United States)

Author keywords

Acetasol HC; Acetic acid; Chinchilla; Ciloxan; Cipro HC; Floxin; Gentamicin; Isolated outer hair cells; Otic drops; Ototoxicity; Tobradex

Indexed keywords

ACETASOL HC; ACETIC ACID; CIPRO HC; CIPROFLOXACIN; CORTISPORIN; DEXAMETHASONE PLUS TOBRAMYCIN; EAR DROPS; GENTAMICIN; HYDROCORTISONE; OFLOXACIN; VOSOL;

ANIMAL CELL; ARTICLE; CELL DEATH; CELL STRUCTURE; CHINCHILLA; COCHLEA; CONTROLLED STUDY; DRUG CYTOTOXICITY; EARDRUM PERFORATION; EXTERNAL OTITIS; HAIR CELL; NONHUMAN; OTOTOXICITY; PRIORITY JOURNAL; TYMPANOSTOMY TUBE;

EID: 0035212262     PISSN: 0023852X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005537-200112000-00004     Document Type: Article

References (15)

1. A double-blind comparative study of ofloxacin otic drops versus neomycinpolymyxin B-hydrocortisone otic drops in the medical treatment of chronic suppurative otitis media
2. Ototoxicity of otic drops applied to the middle ear in the chinchilla
3. Ototoxicity of an ototopical preparation in a primate
4. Ototoxicity of neomycin and Polymyxin B following middle ear application in the chinchilla and baboon
5. Ototoxicity of neomycin and its penetration through the round window membrane into the perilymph
6. Ototoxicity of topical otomicrobial agents
7. Toxicity of ototopical drugs: Animal modeling
8. Effects of common otic preparations on the morphology of isolated cochlear outer hair cells
9. Toxicity of ototopical drugs: Animal modeling
10. Round window membrane. Structure function and permeability: A review
11. Ciprofloxacin: Use as a topical otic preparation
12. The penetration of gentamicin and neomycin into perilymph across the round window membrane
13. Ototoxicity of an ototopic preparation-experimental results and clinical facts
14. Otoacoustic emissions-an approach for monitoring aminoglycoside induced ototoxicity in children
15. The preparation of acetic acid for use in otic drops and its effect on endocochlear potential and pH in inner ear fluid