Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) and CADASIL-like disorders in Japan

Internal Medicine

Volumn 40, Issue 11, 2001, Pages 1075-1076

  Uchino, M ^a  

^a KUMAMOTO UNIV SCHOOL OF MEDICINE   (Japan)

Author keywords

CADASILmutations; Notch3; Vascular dementia

Indexed keywords

NOTCH RECEPTOR;

ADULT; AFFECTIVE NEUROSIS; AGE; AMINO ACID SUBSTITUTION; BRAIN INFARCTION; CELL MEMBRANE; CEREBRAL ARTERY DISEASE; CONTROLLED STUDY; DEMENTIA; DIAGNOSTIC IMAGING; DNA DETERMINATION; EDITORIAL; ELECTRON MICROSCOPY; FACIAL NERVE PARALYSIS; FAMILY HISTORY; GENE MUTATION; GENETIC POLYMORPHISM; HUMAN; IMMUNOHISTOCHEMISTRY; INCIDENCE; JAPAN; LABORATORY TEST; LEUKOENCEPHALOPATHY; MIGRAINE; NUCLEAR MAGNETIC RESONANCE IMAGING; PROTEIN DOMAIN; RISK; SMOOTH MUSCLE FIBER; STROKE;

EID: 0035210860     PISSN: 09182918     EISSN: None     Source Type: Journal    
DOI: 10.2169/internalmedicine.40.1075     Document Type: Editorial

References (12)

1. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy maps to chromosome 19q12
2. Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia
3. Clinical spectrum of CADASIL: A study of 7 families
4. The phenotypic spectrum of CADASIL: Clinical findings in 102 cases
5. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy - Report of an autopsied Japanese case
6. Identification of a notch3 mutation in a Japanese CADASIL family
7. Arg133Cys mutation of notch3 in two unrelated Japanese families with CADASIL
8. CADASIL: Clinical analysis of CADASIL and CADASIL-like disorders in Japan
9. Two Japanese CADASIL families with a R141C mutation in the notch3 gene
10. Hereditary endotheliopathy with retinopathy, nephropathy, and stroke (HERNS)
11. The notch3 intracellular domain repress notch1-mediated activation through Hairy/Enhancer of split (HES) promoters
12. The ectodomain of the notch3 receptor accumulates within the cerebrovasculature of CADASIL patients