Assembly of an FtsZ mutant deficient in GTpase activity has implications for FtsZ assembly and the role of the Z ring in cell division

Journal of Bacteriology

Volumn 183, Issue 24, 2001, Pages 7190-7197

  Mukherjee, A ^a   Saez, C ^a   Lutkenhaus, J ^a  

^a UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID; COPOLYMER; DIETHYLAMINOETHYLDEXTRAN; FTSZ PROTEIN; GENE PRODUCT; GLYCINE; GUANOSINE TRIPHOSPHATASE; GUANOSINE TRIPHOSPHATE; MUTANT PROTEIN; TUBULIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DIVISION; CELL GROWTH; CONTROLLED STUDY; CYTOKINESIS; ENZYME ACTIVITY; EUKARYOTE; GENE MUTATION; GENE OVEREXPRESSION; MOLECULAR STABILITY; NONHUMAN; POLYMERIZATION; PRIORITY JOURNAL; PROKARYOSIS; REDUCTION;

BACTERIAL PROTEINS; CELL DIVISION; CYTOSKELETAL PROTEINS; DEAE-DEXTRAN; ESCHERICHIA COLI; GTP PHOSPHOHYDROLASES; GUANOSINE TRIPHOSPHATE; MUTATION; PROTEIN CONFORMATION; ULTRACENTRIFUGATION;

EID: 0035209228     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.183.24.7190-7197.2001     Document Type: Article

References (41)

1. Sedimentation equilibrium in reacting systems. VI. Some applications to indefinite self-associations. Studies with beta-lactoglobulin A
2. Analysis of ftsZ mutations that confer resistance to the cell division inhibitor SulA (SfiA)
3. Isolation and characterization of ftsZ alleles that affect septal morphology
4. Cell division inhibitors SulA and MinCD prevent formation of the FtsZ ring
5. FtsZ ring structure associated with division in Escherichia coli
6. Bacterial cell division
7. Mutations in ftsZ that confer resistance to SulA affect the interaction of FtsZ with GTP
8. The essential bacterial cell-division protein FtsZ is a GTPase
9. Specific volumes of biological macromolecules and some other molecules of biological interest
10. FtsZ, a prokaryotic homolog of tubulin?
11. Atomic structures of tubulin and FtsZ
12. Bacterial cell division protein FtsZ assembles into protofilament sheets and minirings, structural homologs of tubulin polymers
13. BAD promoter
14. Interaction between FtsZ and inhibitors of cell division
15. Analysis of data from the analytical ultracentrifuge by nonlinear least-squares techniques
16. FtsZ from Escherichia coli, Azotobacter vinelandii, and Thermotoga maritima - Quantitation, GTP hydrolysis, and assembly
17. FtsZ ring in bacterial cytokinesis
18. Bacterial cell division and the Z ring
19. Themes and variations in prokaryotic cell division
20. Dynamic instability of microtubule growth
21. Inhibition of FtsZ polymerization by SulA, an inhibitor of septation in Escherichia coli
22. Escherichia coli cell division protein FtsZ is a guanine nucleotide binding protein
23. Guanine nucleotide-dependent assembly of FtsZ into filaments
24. Dynamic assembly of FtsZ regulated by GTP hydrolysis
25. Purification, assembly, and localization of FtsZ
26. Analysis of FtsZ assembly by light scattering and determination of the role of divalent metal cations
27. Tubulin and FtsZ form a distinct family of GTPases
28. Magnesium-induced linear self-association of the FtsZ bacterial cell division protein monomer. The primary steps for FtsZ assembly
29. Polymerization of Ftsz, a bacterial homolog of tubulin. Is assembly cooperative?
30. Bacterial cell division
31. Substitution of a conserved aspartate allows cation-induced polymerization of FtsZ
32. Non-hydrolysable GTP-gamma-S stabilizes the FtsZ polymer in a GDP-bound state
33. Self-activation of guanosine triphosphatase activity by oligomerization of the bacterial cell division protein FtsZ
34. The self-assembly of long rodlike structures
35. Bacterial SOS checkpoint protein SulA inhibits polymerization of purified FtsZ cell division protein
36. A sedimentation equilibrium study of the association of purine in aqueous solutions
37. The kinetics of microtubule assembly. Evidence for a two-stage nucleation mechanism
38. Analysis of the interaction of FtsZ with itself, GTP, and FtsA
39. The FtsZ protein of Bacillus subtilis is localized at the division site and has GTPase activity that is dependent upon FtsZ concentration
40. Slow polymerization of Mycobacterium tuberculosis FtsZ
41. 2+-mediated GTP-dependent dynamic assembly of bacterial cell division protein FtsZ into asters and polymer networks in vitro