SCOPUS 정보 검색 플랫폼

Volumn 4, Issue 4, 2001, Pages 348-352

A bioreactor with glutamine synthetase-transfected recombinant HepG2 cells exhibits ammonia removal activity without the need for added cofactors and substrates: Advantage of a cellular bioreactor over enzyme-immobilized beads

(8) Enosawa, Shin a Miyashita, Tomoyuki a Li, Xiao Kaug a Suzuki, Seiichi a Amemiya, Hiroshi a Omasa, Takeshi c Suga, Kenichi c Matsumura, Toshiharu b

a NATIONAL RESEARCH INSTITUTE FOR CHILD HEALTH AND DEVELOPMENT (Japan)

b Roman Industries Co Ltd (Japan)

c OSAKA UNIVERSITY (Japan)

Author keywords

Ammonia removal; Glutamine synthetase; HepG2, Bioartificial liver

Indexed keywords

AMMONIA; GLUTAMATE AMMONIA LIGASE; GLUTAMIC ACID; MAGNESIUM ION;

ARTICLE; BIOREACTOR; CELL CULTURE; CELL LINE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CULTURE MEDIUM; ENZYME ACTIVITY; ENZYME IMMOBILIZATION; ENZYME INHIBITION; ENZYME MECHANISM; GENETIC TRANSFECTION; HEMODIALYSIS; HUMAN; HUMAN CELL; LIVER CELL; PRIORITY JOURNAL;

EID: 0035208714 PISSN: 14347229 EISSN: None Source Type: Journal
DOI: 10.1007/BF02480030 Document Type: Article

Times cited : (3)

References (9)

1
- 0017760659
- Formation of amino acid from urea and ammonia by sequential enzyme reaction using a microencapsulated multi-enzyme system
- (1977) Biochem Biophys Res Commun , vol.79 , pp. 24-31
- Cousineau, J.¹ Chang, T.M.²

2
- 0029894845
- Estimation of ammonia removal activity of glutamine synthetase immobilized gel with the aim of selective detoxification of blood ammonia
- (1996) Jpn J Artif Organs , vol.25 , pp. 399-402
- Enosawa, S.¹ Suzuki, S.² Kakefuda, T.³ Amemiya, H.⁴ Omasa, T.⁵ Suga, K.⁶ Ito, N.⁷ Kuramochi, K.⁸

3
- 0033066635
- Removal of digitonin and doxorubicin by multidrug resistance protein-overexpressed cell culture in hollow fiber
- (1999) Kidney Int , vol.56 , pp. 154-163
- Tsuruoka, S.¹ Sugimoto, K.² Ueda, K.³ Suzuki, M.⁴ Imai, M.⁵ Fujimura, A.⁶

4
- 0034529712
- Long-term culture of glutamine synthetase-transfected HepG2 cells in circulatory flow bioreactor for development for a bioartificial liver
- (2000) Cell Transplant , vol.9 , pp. 711-715
- Enosawa, S.¹ Miyashita, T.² Suzuki, S.³ Li, X.K.⁴ Tsunoda, M.⁵ Amemiya, H.⁶ Yamanaka, M.⁷ Hiramatsu, S.⁸ Tanimura, N.⁹ Omasa, T.¹⁰ Suga, K.¹¹ Matsumura, T.¹²

5
- 0035072720
- Application of circulatory flow bioreactor for long-term and large-scale culture of glutamine synthetase transduced CHO cells and its ammonia removal activity with an aim of development for bioartificial liver assist system
- (2001) J Arif Organs , vol.4 , pp. 61-66
- Enosawa, S.¹ Mukaiyama, T.² Miyashita, T.³ Li, X.K.⁴ Suzuki, S.⁵ Amemiya, H.⁶ Matsumura, T.⁷ Omasa, T.⁸ Suga, K.⁹

6
- 0003683777
- U.S. Patent 5270207
- (1993) Circulatory culture equipment
- Matsumura, T.¹ Sawai, Y.² Suzuki, J.³ Fujimori, T.⁴

7
- 0033669829
- Development of bioartificial liver with glutamine synthetase transduced recombinant human hepatoblastom cell line, HepG2
- (2000) Transplant Proc , vol.32 , pp. 2355-2358
- Miyashita, T.¹ Enosawa, S.² Suzuki, S.³ Tamura, A.⁴ Tanaka, H.⁵ Amemiya, H.⁶ Matsumura, T.⁷ Omasa, T.⁸ Suga, K.⁹ Aoki, T.¹⁰ Koyanagi, Y.¹¹

8
- 0030756549
- An attempt to add biological functions by genetic engineering in order to produce high-performance bioreactor cells for hybrid artificial liver: Transfection of glutamine synthetase into Chinese hamster ovary (CHO) cells
- (1997) Cell Transplant , vol.6 , pp. 537-540
- Enosawa, S.¹ Suzuki, S.² Fujino, M.³ Amemiya, H.⁴ Omasa, T.⁵ Urayama, S.⁶ Tanimura, N.⁷ Suga, K.⁸

9
- 0029744279
- Examination of 7-ethoxycoumarin deethylation and ammonia removal activities in 31 hepatocyte cell lines
- (1996) Cell Transplant , vol.5 , pp. 39-41
- Enosawa, S.¹ Suzuki, S.² Kakefuda, T.³ Amemiya, H.⁴

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.