The effect of prinomastat (AG3340), a synthetic inhibitor of matrix metalloproteinases, on posttraumatic proliferative vitreoretinopathy

Ophthalmic Research

Volumn 33, Issue 1, 2001, Pages 20-23

  Ozerdem, Ugur ^a   Mach Hofacre, Beata ^a   Keefe, Kelly ^b   Pham, Tony ^a   Soules, Kelly ^a   Appelt, Krzysztof ^c   Freeman, William R ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b NAVAL MEDICAL CENTER SAN DIEGO   (United States)

^c AGOURON PHARMACEUTICALS INC   (United States)

Author keywords

Matrix metalloproteinase inhibitor; Posttraumatic; Proliferative vitreoretinopathy

Indexed keywords

MATRIX METALLOPROTEINASE INHIBITOR; PRINOMASTAT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; DRUG EFFECT; DRUG SCREENING; FEMALE; MALE; NONHUMAN; PERFORATING EYE INJURY; PRIORITY JOURNAL; RABBIT; RETINA DETACHMENT; SCORING SYSTEM; VITREORETINOPATHY;

EID: 0035208166     PISSN: 00303747     EISSN: None     Source Type: Journal    
DOI: 10.1159/000055636     Document Type: Article

References (18)

1. Eye trauma, the neglected disorder
2. Evolving concepts in the management of posterior segment penetrating ocular injuries
3. Open-globe injury
4. Post-traumatic proliferative vitreoretinopathy
5. Experimental posterior penetrating eye injury in the rabbit (I)
6. Controversies in the management of open-globe injuries involving the posterior segment
7. Controversies in the management of posterior segment ocular trauma
8. Traction retinal detachment: XLIX Edward Jackson Memorial Lecture
9. A prospective study of matrix metalloproteinases in proliferative vitreoretinopathy
10. Predominance of MMP-1 and MMP-2 in epiretinal and subretinal membranes of proliferative vitreoretinopathy
11. The role of matrix metalloproteinases (MMPS) in human retinal pigment epithelial-induced collagen matrix contraction and adhesion to collagen type I
12. Matrix and the retinal pigment epithelium in proliferative retinal disease
13. Structure-based design of MMP inhibitors: Discovery and development of AG3340
14. Intraocular properties of AG3340, a selective matrix metalloproteinase inhibitor with antiangiogenic activity
15. Evaluation of long-term effects of intraocular injections of AG3340, a selective matrix metalloprotease inhibitor
16. A comparison of different cellular inocula in an experimental model of massive periretinal proliferation
17. Experimental posterior penetrating eye injury in the rabbit (II)
18. Experimental double-perforating injury of the posterior segment in rabbit eyes