Kinetic mechanism of DIDS binding to band 3 (AE1) in human erythrocyte membranes

Blood Cells, Molecules, and Diseases

Volumn 27, Issue 5, 2001, Pages 844-849

  Salhany, James M ^a   Schopfer, Lawrence M ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4,4' DIBENZAMIDO 2.2' STILBENEDISULFONATE; 4,4' DIISOTHIOCYANATODIHYDRO 2,2' STILBENEDISULFONATE; 4,4' DIISOTHIOCYANATOSTILBENE 2,2' DISULFONIC ACID; ERYTHROCYTE BAND 3 PROTEIN; STILBENEDISULFONIC ACID; UNCLASSIFIED DRUG; 4 ACETAMIDO 4' ISOTHIOCYANATOSTILBENE 2,2' DISULFONIC ACID; 4,4' DIBENZAMIDO 2,2' STILBENEDISULFONIC ACID; 4,4'-DIBENZAMIDO-2,2'-STILBENEDISULFONIC ACID; DRUG DERIVATIVE;

ANION EXCHANGE; ARTICLE; BINDING KINETICS; COMPETITIVE INHIBITION; COMPUTER MODEL; COMPUTER SIMULATION; CONCENTRATION RESPONSE; CYTOLOGY; DOSE TIME EFFECT RELATION; DRUG PROTEIN BINDING; ERYTHROCYTE KINETICS; ERYTHROCYTE MEMBRANE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; REACTION ANALYSIS; BINDING COMPETITION; CHEMICAL MODEL; DOSE RESPONSE; FLUOROMETRY; KINETICS; METABOLISM; PROTEIN BINDING; TEMPERATURE;

4,4'-DIISOTHIOCYANOSTILBENE-2,2'-DISULFONIC ACID; 4-ACETAMIDO-4'-ISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID; ANION EXCHANGE PROTEIN 1, ERYTHROCYTE; BINDING, COMPETITIVE; COMPUTER SIMULATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ERYTHROCYTE MEMBRANE; FLUOROMETRY; HUMAN; KINETICS; MODELS, CHEMICAL; PROTEIN BINDING; SUPPORT, U.S. GOV'T, NON-P.H.S.; TEMPERATURE;

EID: 0035207098     PISSN: 10799796     EISSN: None     Source Type: Journal    
DOI: 10.1006/bcmd.2001.0458     Document Type: Article

References (14)

1. Chemical probes for anion transporters of mammalian cell membranes
2. - transport site of human red blood cells by kinetic analysis of the inhibitory effector chemical probes
3. Chloride binding to the anion transport site of band 3. A chloride-35 NMR study
4. Anion transport inhibitor binding to band 3 in red blood cell membranes
5. Binding of chloride and disulfonic stilbene transport inhibitor to red cell band 3
6. Quantitative analysis of the kinetics of stilbenedisulfonate binding to band 3
7. Effect of chloride on the binding kinetics of various stilbenedisulfonates to band 3
8. Kinetics of conformational changes associated with inhibitor binding to purified band 3 transporter. Direct observation of allosteric subunit interactions
9. Temperature dependence of anion transport inhibitor binding to human red cell membranes
10. Reversible DIDS binding to band 3 protein in human erythrocyte membranes
11. Allosteric effects in stilbenedisulfonate binding to band 3 protein (AE1)
12. Escherichia coli alkaline phosphatase. Relaxation spectra of ligand binding
13. Stilbenedisulfonate binding kinetics to band 3 (AE1): Relationship between transport and stilbenedisulfonate binding sites, and role of subunit interactions in transport
14. Near-UV circular dichroism of band 3. Evidence for intradomain conformational changes, and interdomain interactions