Reduced flavin: Donor and acceptor enzymes and mechanisms of channeling

Antioxidants and Redox Signaling

Volumn 3, Issue 5, 2001, Pages 881-897

  Tu, S C ^a  

^a University of Houston   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLAVIN REDUCTASE; FLAVOPROTEIN; LUCIFERASE; OXIDOREDUCTASE; QUERCETIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; UNCLASSIFIED DRUG;

CATALYSIS; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME SPECIFICITY; ENZYME SUBSTRATE; PRIORITY JOURNAL; REVIEW; VIBRIO HARVEYI;

VIBRIO HARVEYI;

EID: 0035205486     PISSN: 15230864     EISSN: None     Source Type: Journal    
DOI: 10.1089/15230860152665046     Document Type: Review

References (100)

1. Flavoprotein monooxygenases
2. Two-component flavin-dependent pyrrole-2-carboxylate monooxygenase from Rhodococcus sp
3. Cloning and analysis of structural genes from Streptomyces pristinaespiralis encoding enzymes involved in the conversion of pristinamycin IIB to pristinamycin IIA (PIIA): PIIA synthase and NADH: riboflavin 5′-phosphate oxidoreductase
4. Studies on Escherichia coli chorismate synthase
5. Refined crystal structure of spinach ferredoxin reductase at 1.7 Å resolution: Oxidized, reduced and 2′-phospho-5′-AMP bound states
6. Cloning and nucleotide sequence of a cDNA of the human erythrocyte NADPH-flavin reductase
7. Catalytically active forms of the individual subunits of Vibrio harveyi luciferase and their kinetic and binding properties
8. Nucleotide sequence of the luxA gene of Vibrio harveyi and the complete amino acid sequence of the a subunit of bacterial luciferase
9. Reduction and mobilization of iron by a NAD(P)H: Flavin oxidoreductase from Escherichia coli
10. Enzymic and chemical reduction of the iron center of the Escherichia coli ribonucleotide reductase protein R2. The role of the C-terminus
11. Flavin mononucleotide reductase of luminous bacteria
12. The chemistry of a 1,5-diblocked flavin. 2. Proton and electron transfer steps in the reaction of dihydroflavins with oxygen
13. The mechanism and substrate specificity of the NADPH: Flavin oxidoreductase from Escherichia coli
14. The 1.5-Å resolution crystal structure of bacterial luciferase in low salt conditions
15. Analysis of a trimeric complex involving chorismate synthase from Bacillus subtilis
16. NAD(P)H: Flavin oxidoreductase of Escherichia coli. A ferric iron reductase participating in the generation of the free radical of ribonucleotide reductase
17. Enzymatic regulation of the radical content of the small subunit of Escherichia coli ribonucleotide reductase involving reduction of its redox centers
18. Ferric reductases or flavin reductases?
19. Nucleotide sequence of the luxA and luxB genes of the bioluminescent marine bacterium Vibrio fischeri
20. Functional analysis of the small component of the 4-hydroxyphenylacetate 3-monooxygenase of Escherichia coli W: A prototype of a new flavin: NAD(P)H reductase subfamily
21. The NAD(P)H: Flavin oxidoreductase from Escherichia coli as a source of superoxide radicals
22. Identification of NADH-specific and NADPH-specific FMN reductases in Beneckea harveyi
23. The oxidation of reduced flavin mononucleotide by molecular oxgen
24. Molecular mechanisms of biocatalytic desulfurization of fossil fuels
25. 2
26. Purification and characterization of NADPH-dependent flavin reductase. An enzyme required for the activation of chorismate synthase in Bacillus subtilis
27. The oxygenated bacterial luciferase-flavin intermediate. Reaction products via the light and dark pathways
28. Spectral properties of an oxygenated luciferase-flavin intermediate isolated by low-temperature chromatography
29. Biochemistry and physiology of bioluminescent bacteria
30. Crystal structure of NADH oxidase from Thermus thermophilus
31. Identification and characterization of a catalytic base in bacterial luciferase by chemical rescue of a dark mutant
32. Crystal structure of NAD(P)H: Flavin oxidoreductase from Escherichia coli
33. NAD(P)H-flavin oxidoreductase from the bioluminescent bacterium, Vibrio fischeri ATCC 7744, is a flavoprotein
34. Purification and properties of the NADH and NADPH specific FMN oxidoreductases from Beneckea harveyi
35. Studies of the control of luminescence in Beneckea harveyi: Properties of the NADH and NADPH:FMN oxidoreductases
36. Identification and Characterization of Interactions Between NAD(P)H:FMN Oxidoredoctase and Luciferase
37. Differential transfers of reduced flavin cofactor and product by bacterial flavin reductase to luciferase
38. Nucleotide sequence of the luxB gene of Vibrio harveyi and the complete amino acid sequence of the β subunit of bacterial luciferase
39. The catalytic mechanism of DNA photolyase
40. Role of flavoproteins in light-dependent reactions
41. Identification of a flavin: NADH oxidoreductase involved in the biosynthesis of actinorhodin. Purification and characterization of the recombinant enzyme
42. Identification of a monooxygenase from Streptomyces coelicolor A3(2) involved in biosynthesis of actinorhodin: Purification and characterization of the recombinant enzyme
43. Overexpression of the bifunctional chorismate synthase of Neurospora crassa
44. Structure and site-directed mutagenesis of a flavoprotein from Escherichia coli that reduces nitrocompounds. Alteration of pyridine nucleotide binding by a single amino acid substitution
45. 1.8 Å crystal structure of the major NAD(P)H:FMN oxidoreductase of a bioluminescent bacterium, Vibrio fischeri: Overall structure, cofactor and substrate-analog binding, and comparison with related flavoproteins
46. Characterization and postulated structure of the primary emitter in the bacterial luciferase reaction
47. Isolation and characterization of the transient, luciferase-bound flavin-4a-hydroxide in the bacterial luciferase reaction
48. Affinity purification of bacterial luciferase and NAD(P)H: FMN oxidoreductases by FMN-Sepharose for analytical applications
49. Gene overexpression, purification, and identification of a desulfurization enzyme from Rhodococcus sp. strain IGTS8 as a sulfide/sulfoxide monooxygenase
50. Mechanism of reduced flavin transfer from Vibrio harveyi NADPH-FMN oxidoreductase to luciferase
51. Mechanism of aldehyde inhibition of Vibrio harveyi luciferase. Identification of two aldehyde sites and relationship between aldehyde and flavin binding
52. Vibrio harveyi NADPH-flavin oxidoreductase: Cloning, sequencing and overexpression of the gene and purification and characterization of the cloned enzyme
53. Effects of mutations of the αHis 45 residue of Vibrio harveyi luciferase on the yield and reactivity of the flavin peroxide intermediate
54. The turnover of bacterial luciferase is limited by a slow decomposition of the ternary enzyme-product complex of luciferase, FMN, and fatty acid
55. Vibrio harveyi NADPH:FMN oxidoreductase: Preparation and characterization of the apoenzyme and monomerdimer equilibrium
56. Role of reduced FMN in the catalytic mechanism of chorismate synthase
57. On the reaction of reduced flavins with molecular oxygen
58. Bacterial bioluminescence: Spectral study of the emitters in the in vitro reaction
59. The effect of flavin isomers and analogues upon the color of bacterial bioluminescence
60. + reductase family? Evidence for the catalytic role of serine 49 residue
61. Reaction of NAD(P)H:flavin oxidoreductase from Escherichia coli with NADPH and riboflavin. Identification of intermediates
62. The NAD(P)H:flavin oxidoreductase from Escherichia coli. Evidence for a new mode of binding for reduced pyridine nucleotides
63. Elucidation of the metabolic pathway for dibenzothiophene desulphurization by Rhodococcus sp. strain IGTS8 (ATCC 53968)
64. An NADPH:FAD oxidoreductase from the valanimycin producer, Streptomyces viridifaciens. Cloning, analysis, and overexpression
65. Purification and characterization of isobutylamine N-hydroxylase from the valanimycin producer Streptomyces viridifaciens MG 456hF10
66. Purification and characterization of EDTA monooxygenase from the EDTA-degrading bacterium BNC 1
67. Molecular characterization of 4-hydroxyphenylacetate 3-hydroxylase of Escherichia coli. A two-protein component enzyme
68. Flavin reductase: Sequence of cDNA from bovine liver and tissue distribution
69. Evidence that the protein components of bovine erythrocyte green heme binding protein and flavin reductase are identical
70. Action mechanism of Escherichia coli DNA photolyase. III. Photolysis of the enzyme-substrate complex and the absolute action spectrum
71. Characterization of the flavin reductase gene (fre) of Escherichia coli and construction of a plasmid for overproduction of the enzyme
72. Flavin reductase P: Structure of a dimeric enzyme that reduces flavin
73. 2 homodimer: Implications for flavin binding
74. Unusual folded conformation of nicotinamide adenine dinucleotide bound to flavin reductase P
75. Purification of the two-enzyme system catalyzing the oxidation of the D- proline residue of pristinamycin IIB during the last step of pristinamycin IIA biosynthesis
76. 2 homodimer of bacterial luciferase from Vibrio harveyi: X-ray analysis of a kinetic protein folding trap
77. Isolation and properties of bacterial luciferase-oxygenated flavin intermediate complexed with long-chain alcohols
78. Isolation and properties of bacterial luciferase intermediates containing different oxygenated flavins
79. Physical interaction and activity coupling between two enzymes induced by immobilization of one
80. Biochemistry of bacterial bioluminescence
81. Kinetic studies on the mechanism of bacterial NAD(P)H:Flavin oxidoreductase
82. Characterization of Vibrio harveyi NADPH:FMN oxidoreductase and mechanism of reduced flavin transfer to luciferase
83. Purification and characterization of a two-component monooxygenase that hydroxylates nitrilotriacetate from "Chelatobacter" strain ATCC 29600
84. Bacterial luciferase: A carbon-13, nitrogen-15, and phosphorus-31 nuclear magnetic resonance investigation
85. Individual α and β subunits of bacterial luciferase exhibit bioluminescence activity
86. Vibrio harveyi NADPH-FMN oxidoreductase Arg 203 as a critical residue for NADPH recognition and binding
87. Specificities and properties of three reduced pyridine nucleotide-flavin mononucleotide reductases coupling to bacterial luciferase
88. Identification and characterization of the two-enzyme system catalyzing oxidation of EDTA in the EDTA-degrading bacterial strain DSM 9103
89. Functional consequences of site-directed mutation of conserved histidyl residues of the bacterial luciferase α subunit
90. Cloning, sequencing, and analysis of a gene cluster from Chelatobacter heintzii ATCC 29600 encoding nitrilotriacetate monooxygenase and NADH:flavin mononucleotide oxidoreductase
91. Characterization of 4-hydroxyphenylacetate 3-hydroxylase (HpaB) of Escherichia coli as a reduced flavin adenine dinucleotideutilizing monooxygenase
92. Characterization of the purified NADPH-flavin reductase of human erythrocytes
93. Identification of the genes encoding NAD(P)H-flavin oxidoreductases that are similar in sequence to Escherichia coli Fre in four species of luminous bacteria: Photorhabdus luminescens, Vibrio fischeri, Vibrio harveyi, and Vibrio orientalis
94. Identification of the gene encoding the major NAD(P)H-flavin oxidoreductase of the bioluminescent bacterium Vibrio fischeri ATCC 7744
95. Biochemical characterization of NfsA, the Escherichia coli major nitroreductase exhibiting a high amino acid sequence homology to Frp, a Vibrio harveyi flavin oxidoreductase
96. Conversion of NfsB, a minor Escherichia coli nitroreductase, to a flavin reductase similar in biochemical properties to FRase I, the major flavin reductase in Vibrio fischeri, by a single amino acid substitution
97. Gene cloning, purification, and characterization of NfsB, a minor oxygen-insensitive nitroreductase from Escherichia coli, similar in biochemical properties to FRase I, the major flavin reductase in Vibrio fischeri
98. Conversion of NfsA, the major Escherichia coli nitroreductase, to a flavin reductase with an activity similar to that of Frp, a flavin reductase in Vibrio harveyi, by a single amino acid substitution
99. Purification and characterization of NfsA1, a Bacillus subtilis nitro/flavin reductase capable of interacting with the bacterial luciferase