Inhibition of sorbitol dehydrogenase exacerbates autonomic neuropathy in rats with streptozotocin-induced diabetes

Journal of Neuropathology and Experimental Neurology

Volumn 60, Issue 12, 2001, Pages 1153-1169

  Schmidt, Robert E ^a   Dorsey, Denise A ^a   Beaudet, Lucie N ^a   Plurad, Santiago B ^a   Parvin, Curtis A ^a   Yarasheski, Kevin E ^a   Smith, Samuel R ^a   Lang, Hans Jochen ^b   Williamson, Joseph R ^a   Ido, Yasuo ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b SANOFI AVENTIS DEUTSCHLAND GMBH   (Germany)

Author keywords

Diabetic neuropathy; Sorbitol pathway; Sympathetic neuroaxonal dystrophy

Indexed keywords

ENZYME INHIBITOR; FRUCTOSE; IDITOL DEHYDROGENASE; SDI 157; SDI 158; SORBINIL; SORBITOL; STREPTOZOCIN; TYROSINE 3 MONOOXYGENASE; UNCLASSIFIED DRUG; ZOPOLRESTAT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTONOMIC NEUROPATHY; CONTROLLED STUDY; DIABETES MELLITUS; DIABETIC NEUROPATHY; ENZYME INHIBITION; ENZYME LOCALIZATION; MESENTERY; MYENTERIC PLEXUS; NEUROAXONAL DYSTROPHY; NONHUMAN; NORADRENERGIC NERVE; POSTGANGLIONIC NERVE; PRIORITY JOURNAL; RAT; STREPTOZOCIN DIABETES; SUPERIOR CERVICAL GANGLION; SYMPATHETIC GANGLION; ULTRASTRUCTURE;

EID: 0035205459     PISSN: 00223069     EISSN: None     Source Type: Journal    
DOI: 10.1093/jnen/60.12.1153     Document Type: Article

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