The protective effect of hepatocyte growth-promoting factor (pHGF) against hydrogen peroxide-induced acute lung injury in rats

Medical Electron Microscopy

Volumn 34, Issue 2, 2001, Pages 92-102

  Liu, X L ^a   Sato, Shigeru ^a   Dai, Wei ^a   Yamanaka, Nobuaki ^a  

^a NIPPON MEDICAL SCHOOL   (Japan)

Author keywords

Hydrogen peroxide; Lung injury; Morphology; pHGF

Indexed keywords

HYDROGEN PEROXIDE; SCATTER FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; ATELECTASIS; BLOOD LEVEL; CAPILLARY ENDOTHELIUM; CELL MEMBRANE; CONTROLLED STUDY; DEVICE; ELECTRON MICROSCOPY; ENDOTHELIUM CELL; INFLAMMATORY CELL; LUNG ALVEOLUS CELL TYPE 1; LUNG ALVEOLUS CELL TYPE 2; LUNG EDEMA; LUNG INJURY; MALE; MEMBRANE DAMAGE; MICROSCOPY; MICROVILLUS; MITOCHONDRION; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTECTION; RAT;

ANIMALS; APOPTOSIS; CELL MEMBRANE; ENDOTHELIUM, VASCULAR; EPITHELIUM; HEPATOCYTE GROWTH FACTOR; HYDROGEN PEROXIDE; IN SITU NICK-END LABELING; LIPID PEROXIDES; LUNG DISEASES; MICROSCOPY, ELECTRON; PULMONARY ALVEOLI; PULMONARY EDEMA; RATS; TIME FACTORS;

EID: 0035205212     PISSN: 09184287     EISSN: None     Source Type: Journal    
DOI: 10.1007/s007950170003     Document Type: Article

References (46)

1. Causes of mortality in patients with the adult respiratory distress syndrome
2. Clinical risks for development of the acute respiratory distress syndrome
3. Endotoxin and lung injury
4. Biology of disease. Free radicals and tissue injury
5. Davis conference: Oxygen radicals and human disease
6. Autooxidative damage in Behcet's disease: Endothelial cell damage following the elevated oxygen radicals generated by stimulated neutrophils
7. Evaluation of tissue indicators of oxidative stress in rat treated chronically with adriamycin
8. Superoxide radical-mediated endothelial injury and vasoconstriction of rat thoracic aortic rings
9. Lesion of aortic intima caused by intravenous administration of linoeic acid hydroperoxide
10. Treatment of gram-negative bacteremia and septic shock with HA-1A human monoclonal antibody against endotoxin. A randomized, double-blind, placebocontrolled trial
11. Role of the intercellular adhesion molecule-1 (ICAM-1) in endotoxin-induced pneumonia evaluated using ICAM-1 antisense oligonucleotides, anti-ICAM-1 monoclonal antibodies, and ICAM-1 mutant mice
12. Requirement and role of C5a in acute lung inflammatory injury in rats
13. A trial of antioxidants Nacetylcysteine and procysteine in ARDS
14. Protection from lethal apoptosis in lipopolysaccharide-induced acute lung injury in mice by a caspase inhibitor
15. Hepatocytes growth factor: Molecular structure, roles in liver regeneration and other biological functions
16. In vivo mitogenic action of HGF on lung epithelial cells: Pulmotrophic role in lung regeneration
17. Hepatocyte growth factor is a mitogen for alveolar type II cells in rat lavage fluid
18. Hepatocyte growth factor and keratinocyte growth factor in the pulmonary edema fluid of patients with acute lung injury
19. Simultaneous or delayed administration of hepatocyte growth factor equally represses the fibrotic changes in murine lung injury induced by bleomycin
20. Evaluation of hepatocyte growth-promoting factors in treating 1687 cases of fulminant hepatitis
21. Purification and characterization of a growth factor from rat platelets for mature parenchymal hepatocytes in primary cultures
22. Purification and physicochemical characterization of hepatic stimulator
23. Molecular cloning and sequence analysis of the cDNA for a human serine protease responsible for activation of hepatocyte growth factor. Structural similarity of the protease precursor to blood coagulation factor XII
24. The protective effect of hepatocyte growth-promoting factor (pHGF) against carbon tetrachloride-induced acute liver injury in rats: An ultrastructural study
25. Ultrastructural damages in rat myocardium induced by hydrogen peroxide injection
26. A simple fluorometric assay for lipoperoxide in blood plasma
27. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
28. Liposome oxidation and erythrocyte lysis by enzymically generated superoxide and hydrogen peroxide
29. Damage to microsomal membrane by lipid peroxidation
30. Regulation and deterioration of structure in membranes
31. Lipid peroxidation: Its measurement, occurrence, and significance in animal tissues
32. Apoptosis by death factor
33. Role of mesenchymal cell death in lung remodeling after injury
34. Ultrastructure of multinucleated giant cell apoptosis in foreign-body granuloma
35. Endothelial cell apoptosis in lipopolysaccharide-induced lung injury in mice
36. BCL-2 functions in an antioxidant pathway to prevent apoptosis
37. Oxidative stress-induced apoptosis prevented by trolox
38. Apoptosis induced by oxysterols in murine lymphoma cells and in normal thymocytes
39. Free oxygen radicals decrease electrical resistance of micro-vascular endothelium in brain
40. In vivo infusion of oxygen free radical substrates causes myocardial systolic, but not diastolic dysfunction
41. An ultrastructural study of the lung in an experimental model of ARDS with special reference to alterations of the alveolar-capillary membrane
42. Toxicity of fatty ozonides and peroxides
43. Observations on the role of vitamin E in the toxicity of oxidized fats
44. Toxic effects of hydroperoxide injections on rat lung
45. Short-term exposure to nitrogen dioxide: Effects on pulmonary ultrastructure, compliance, and the surfactant system
46. Apoptosis vs nonapoptotic cytotoxicity induced by hydrogen peroxide