Frequency of BRCA1 and BRCA2 germline mutations in Japanese breast cancer families

International Journal of Cancer

Volumn 91, Issue 1, 2001, Pages 83-88

  Ikeda, Noriko ^a   Miyoshi, Yasuo ^a   Yoneda, Kohri ^a   Shiba, Eiichi ^a   Sekihara, Yoshizo ^b   Kinoshita, Moritoshi ^b   Noguchi, Shinzaburo ^a  

^a OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

^b Otsuka Assay Laboratories   (Japan)

Author keywords

BRCA1 and BRCA2; Breast cancer

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN;

ADULT; ARTICLE; BREAST CANCER; CANCER FAMILY; CAUCASIAN; FEMALE; FRAMESHIFT MUTATION; GENE FREQUENCY; GENE MUTATION; GENETIC RISK; HAPLOTYPE; HETEROZYGOTE; HUMAN; HUMAN CELL; JAPAN; MAJOR CLINICAL STUDY; NONSENSE MUTATION; PRIORITY JOURNAL;

ADULT; AGED; BRCA2 PROTEIN; BREAST NEOPLASMS; BREAST NEOPLASMS, MALE; CODON; CODON, NONSENSE; DNA MUTATIONAL ANALYSIS; FAMILY HEALTH; FEMALE; FRAMESHIFT MUTATION; GENE DELETION; GENES, BRCA1; GERM-LINE MUTATION; HAPLOTYPES; HUMANS; JAPAN; MALE; MIDDLE AGED; NEOPLASM PROTEINS; OVARIAN NEOPLASMS; POLYMORPHISM, GENETIC; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; TRANSCRIPTION FACTORS;

EID: 0035203330     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-0215(20010101)91:1<83::AID-IJC1013>3.0.CO;2-5     Document Type: Article

References (24)

1. A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1
2. Localization of a breast cancer susceptibility gene, BRCA2, to chromosome 13q12-13
3. Genetic linkage analysis in familial breast and ovarian cancer: Results from 214 families
4. An evaluation of genetic heterogeneity in 145 breast-ovarian cancer families
5. BRCA1 mutations and breast cancer in the general population
6. BRCA1 sequence analysis in women at high risk for susceptibility mutations
7. Frequency of breast cancer attributable to BRCA1 in a population-based series of American women
8. BRCA1 mutations in women attending clinics that evaluate the risk of breast cancer
9. Sequence analysis of BRCA1 and BRCA2: Correlation of mutations with family history and ovarian cancer risk
10. Prevalence of BRCA1 and BRCA2 gene mutations in patients with early-onset breast cancer
11. Prevalence and penetrance of BRCA1 and BRCA2 gene mutations in unselected Ashkenazi Jewish women with breast cancer
12. Probability of carrying a mutation of breast-ovarian cancer gene BRCA1 based on family history
13. BRCA1 mutations in Ashkenazi Jewish women
14. BRCA1 mutations in Jewish and non-Jewish women with early-onset breast cancer
15. Germline mutation of BRCA1 in Japanese breast cancer families
16. BRCA2 germline mutations in Japanese breast cancer families
17. Mutational analysis of BRCA1 gene in ovarian and breastovarian cancer families in Japan
18. High proportion of missense mutations of the BRCA1 and BRCA2 genes in Japanese breast cancer families
19. The 1993-94 Genethon human genetic linkage map
20. Loss of heterozygosity in BRCA1 and BRCA2 markers and high-grade malignancy in breast cancer
21. Differential contributions of BRCA1 and BRCA2 to early-onset breast cancer
22. Variation of risks of breast and ovarian cancer associated with different germline mutations of the BRCA2 gene
23. Nonsense mutation at codon 63 of the BRCA1 gene in Japanese breast cancer patients
24. Clinicopathologic analysis of BRCA1- or BRCA2-associated hereditary breast carcinoma in Japanese women