Hypofrontality and negative symptoms in schizophrenia: Synthesis of the anatomical and neuropsychological knowledge and ecological perspectives;Hypofrontalité et symptômes négatifs dans la schizophrénie: Synthèse des acquis anatomiques et neuropsychologiques et perspectives écologiques

Encephale

Volumn 27, Issue 5, 2001, Pages 405-415

  Semkovska, M ^a   Bedard M A ^a   Stip, E ^a  

^a CENTRE DE RECHERCHE FERNAND SEGUIN   (Canada)

Author keywords

Cognition; Daily living; Executive deficits; Hypofrontality; Negative symptoms; Rehabilitation; Schizophrenia

Indexed keywords

ARTICLE; BRAIN CORTEX LESION; DAILY LIFE ACTIVITY; DISEASE ASSOCIATION; FRONTAL LOBE; FUNCTIONAL ASSESSMENT; HUMAN; NEGATIVE SYNDROME; NEUROPATHOLOGY; NEUROPSYCHOLOGICAL TEST; PATHOLOGICAL ANATOMY; SCHIZOPHRENIA; TASK PERFORMANCE;

ACTIVITIES OF DAILY LIVING; ATROPHY; CEREBRAL VENTRICLES; DEPRESSION; DIAGNOSTIC IMAGING; FRONTAL LOBE; HUMANS; NEUROPSYCHOLOGICAL TESTS; PROGNOSIS; PSYCHIATRIC STATUS RATING SCALES; SCHIZOPHRENIA; SCHIZOPHRENIC PSYCHOLOGY;

EID: 0035202948     PISSN: 00137006     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (100)

1. Neurocognitive and social functioning in schizophrenia
2. Childhood-onset schizophrenia: Biological markers in relation to clinical characteristics
3. Magnetic resonance imaging of the brain in schizophrenia: The pathophysiologic significance of structural abnormalities
4. Evaluation of positive and negative symptoms in schizophrenia
5. Structural abnormalities in the frontal system in schizophrenia: A magnetic resonance imaging study
6. Negative v positive schizophrenia: Definition and validation
7. Hypofrontality in neuroleptic-naive patients and in patients with chronic schizophrenia. Assessment with Xenon 133 single-photon emission CT and the Tower of London
8. Ventricular enlargement in schizophrenia: Definition and prevalence
9. The distinction of positive and negative symptoms in schizophrenia: The failure of a two-dimentional model
10. Quality of life and response of negative symptoms in schizophrenia to haloperidol and atypical antipsychotic remoxipride
11. Auditory hallucinations and smaller superior temporal gyral volume in schizophrenia
12. The illusion of reality: A review and integration of psychological research on hallucinations
13. Regional cerebral blood flow in monozygotic twins discordant and concordant for schizophrenia
14. Brain morphology and schizophrenia. A magnetic resonance imaging study of limbic, prefrontal cortex, and caudate structures
15. Glucose metabolic rate in normals and schizophrenics during the continuous performance test assessed by positron emission tomography
16. Striatal metabolic rate and clinical response to neuroleptics in schizophrenia
17. Aspects of stability of regional cerebral blood flow in chronic schizophrenia: A 18-year follow-up study
18. Schizophrenia, a brain disease? A clinical review of structural and functional cerebral abnormality in the disorder
19. Impaired attention, genetics and the pathophysiology of schizophrenia
20. De la validité écologique en neuropsychologie
21. Molecular pathology of schizophrenia: More than one disease process?
22. Reduction in temporal size in siblings with schizophrenia: A magnetic resonance imaging study
23. Volumes of ventricular system subdivisions measured from magnetic resonance images in first-episode schizophrenic patients
24. Towards a neuropsychology of schizophrenia
25. Regional brain activity in chronic schizophrenic patients during the performance of verbal fluency task
26. Relationships between changes in symptom ratings, neuropsychological test performance and quality of life in schizophrenic patients treated with clozapine
27. Supplementary motor area structure and function: Review and hypotheses
28. Probing prefrontal function in schizophrenia with neuropsychological paradigms
29. Cerebral ventricular size and neuropsychological impairment in young chronic schizophrenics
30. The neuropsychology of schizophrenia
31. What are the functional consequences of neurocognitive deficits in schizophrenia?
32. Reduced dorsal and orbital prefrontal grey matter volumes in schizophrenia
33. Brain function in psychiatric disorders: III. Regional cerebral blood flow in unmedicated schizophrenics
34. Relation among clinical scales in schizophrenia
35. Risperidone: An analysis of the first three years in general use
36. Planification de l'action et communication schizophrenique
37. The influence of neurocognitive deficits and symptoms on quality of life in schizophrenia
38. Functional neuroimaging in schizophrenia: Symptoms, treatment, and aetiology
39. Stability of CT scan findings in schizophrenia: Results of an 8 years follow-up study
40. Distribution of cerebral activity in chronic schizophrenia
41. Neuropsychiatric rehabilitation for persistent mental illness
42. X-ray computed tomography and magnetic resonance imaging in psychiatry
43. Cerebral ventricular size and cognitive impairment in chronic schizophrenia
44. Tolérance aux neuroleptiques, déficit et fonctions cognitives
45. Three clinical syndromes of schizophrenia in untreated subjects: Relations to brain glucose activity measured by positron emission tomography
46. SPECT analysis of regional cerebral blood flow changes in patients with schizophrenia during the Wisconsin card sorting test
47. Computerised tomography in schizophrenia 15 years on
48. Schizophrenic syndromes, cognitive performance and neurological dysfunction
49. The symptoms of chronic schizophrenia: A re-examination of the positive-negative dichotomy
50. The multidimentional phenotype of schizophrenia
51. Syndromes of chronic schizophrenia
52. Patterns of cerebral blood flow in schizophrenia
53. Schizophrenic syndromes and frontal lobe performance
54. Wisconsin card sorting test and work performance in schizophrenia
55. Social skills at work: Deficits and predictors of improvement in schizophrenia
56. Executive-frontal lobe cognitive dysfunction in schizophrenia: A symptom subtype analysis
57. Assessment of frontal lobe functions
58. Imageríe cėrébrale des psychoses schizophréniques
59. Electron microscopic study of schizophrenia
60. Frontal and non-frontal lobe neuropsychological test performance and clinical symptomatology in schizophrenia
61. Symptoms and cognition as predictors of community functioning: A prospective analysis
62. Information processing and attentional functioning in the developmental course of schizophrenic disorders
63. The relationship of minor physical anomalies and other putative indices of developmental disturbance in schizophrenia to abnormalities of cerebral structure on magnetic resonance imaging
64. Frontal-striatal cognitive deficits in patients with chronic schizophrenia
65. Schizophrenics show spatial working memory deficits
66. Two cortical systems for directing movement
67. Lateral ventricular enlargement associated with persistent unemployment and negative symptoms in both schizophrenia and bipolar disorder
68. Are there more than two syndromes in schizophrenia? A critique of the positive-negative dichotomy
69. Independent frontal system deficits in schizophrenia: Cognitive, clinical and adaptive implications
70. Executive impairment among the functionally dependent: Comparisons between schizophrenic and elderly subjects
71. Neurobiological findings in first admission patients with or schizophreniform disorder
72. Neuropsychological deficits in neuroleptic naive patients with first-episode schizophrenia
73. Subsyndromes in chronic schizophrenia: Do their psychopathological characteristics correspond to cerebral alterations?
74. The relative influences of symptoms, insight, and neurocognition on social adjustment in schizophrenia and schizoaffective disorder
75. Anatomical abnormalities in the brains of monozygotic twins discordant for schizophrenia
76. Limbic system abnormalities identified in schizophrenia using positron emission tomography with fluorodeoxyglucose and neocortical alterations with deficit syndrome
77. A contribution to the morphological background of schizophrenia
78. Cerebral blood flow activation and functional lesion in schizophrenia
79. Do semantic priming effects correlate with sensory gating in schizophrenia?
80. Cerebral ventricular abnormalities in schizophrenia: Evidence of their early origin and stability over time
81. Schizophrenia and the frontal lobes
82. A connectionist approach to the prefrontal cortex
83. Prefrontal cortex dysfunction in schizophrenia
84. Physiological dysfunction of dorsolateral prefrontal cortex in schizophrenia. I: Regional cerebral blood flow evidence
85. Cerebral ventricular enlargement in chronic schizophrenia: An association with poor response to therapy
86. Lateral cerebral ventricular enlargement in chronic schizophrenia
87. Prefrontal cortex and schizophrenia: A quantitative magnetic resonance imaging study
88. Cognition and control of action in psychopathology
89. Exploration des activités cognitives dans la schizophrénie
90. Hypofrontality in schizophrenia: A review of the evidence
91. Negative symptoms and hypofrontality in chronic schizophrenia
92. Brain volume loss in schizophrenia: When does it occur and is it progressive?
93. Functional magnetic resonance imaging of schizophrenic patients and comparison subjects during word production
94. Widespread cerebral grey matter volume deficits in schizophrenia
95. Schizophrenia and the frontal brain: A quantitative review