The action of high-dose factor VIIa (FVIIa) in a cell-based model of hemostasis

Seminars in Hematology

Volumn 38, Issue 4 SUPPL. 12, 2001, Pages 6-9

  Hoffman, Maureane ^a   Monroe III, Dougald M ^a,b  

^a DURHAM VA MEDICAL CENTER   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 10; BLOOD CLOTTING FACTOR 10A; BLOOD CLOTTING FACTOR 7A; RECOMBINANT BLOOD CLOTTING FACTOR 7A; THROMBIN; THROMBOPLASTIN;

BLOOD CELL; BLOOD CLOTTING; CONFERENCE PAPER; DOSE RESPONSE; DRUG MEGADOSE; HEMOPHILIA; HEMOSTASIS; HUMAN; PRIORITY JOURNAL; THROMBOCYTE ACTIVATION; THROMBOCYTE MEMBRANE;

EID: 0035200558     PISSN: 00371963     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0037-1963(01)90140-4     Document Type: Conference Paper

References (13)

1. The effect of factor X level on thrombin generation and the procoagulant effect of activated factor VII in a cell-based model of coagulation
2. Prothrombin is a cofactor for the binding of factor XI to the platelet surface and for platelet-mediated factor XI activation by thrombin
3. Waterfall sequence for intrinsic blood clotting
4. Factor XI activation in a revised model of blood coagulation
5. Activated factor VII activates factors IX and X on the surface of activated platelets: Thoughts on the mechanism of action of high-dose activated factor VII
6. Factors IXa and Xa play distinct roles in tissue factor-dependent initiation of coagulation
7. A possible mechanism of action of activated factor VII independent of tissue factor
8. Activation of a proteolytic system by a membrane lipoprotein: Mechanism of action of tissue factor
9. The tissue factor pathway of blood coagulation
10. Thrombin activates factor XI on activated platelets in the absence of factor XII
11. Activation of factor IX by the reaction product of tissue factor and factor VII: Additional pathway for initiating blood coagulation
12. Hemophilia as a defect of the tissue factor pathway of blood coagulation: Effect of factors VIII and IX on factor X activation in a continuous-flow reactor
13. Inhibition of thrombin generation by the zymogen factor VII: Implications for the treatment of hemophilia A by factor VIIa