Effect of long-term, low-dose acyclovir suppressive therapy on susceptibility to acyclovir and frequency of acyclovir resistance of herpes simplex virus type 2

Antiviral Chemistry and Chemotherapy

Volumn 12, Issue 4, 2001, Pages 233-239

  Honda, M ^a   Okuda, T ^a   Hasegawa, T ^a   Kurokawa, M ^a   Shiraki, K ^a   Matsuo, K ^a   Komatsuzaki, M ^a   Niimura, M ^a  

^a JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Acyclovir; Genital herpes; Herpes simplex virus; Susceptibility

Indexed keywords

ACICLOVIR; IDOXURIDINE; PHOSPHONOACETIC ACID; THYMIDINE KINASE;

ADULT; AGED; ANIMAL CELL; ANTIBIOTIC RESISTANCE; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; ENZYME DEFICIENCY; FEMALE; GENITAL HERPES; HERPES SIMPLEX; HERPES SIMPLEX VIRUS 2; HUMAN; INCIDENCE; MAJOR CLINICAL STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; RECURRENT DISEASE; VERO CELL; VIRUS CULTURE; VIRUS ISOLATION; VIRUS REPLICATION;

EID: 0035197014     PISSN: 09563202     EISSN: None     Source Type: Journal    
DOI: 10.1177/095632020101200404     Document Type: Article

References (32)

1. Susceptibility of HSV strains from patients with genital herpes treated with various formulations of acyclovir
2. Long-term suppressive therapy with acyclovir for recurrent genital herpes
3. Once-daily varacyclovir hydrochloride for suppression of recurrent genital herpes
4. Management of acyclovir-resistant herpes simplex and varicella-zoster virus infection
5. In vitro susceptibility of varicella-zoster virus to acyclovir
6. 1998 Guidelines for treatment of sexually transmitted diseases
7. Survey of resistance of herpes simplex virus to acyclovir in northwest England
8. Growth inhibition by acycloguanosine of herpesviruses isolated from human infection
9. Selectivity of action of an antiherpetic agent, 9-(2-hydroxyethoxymethyl) guanine
10. Herpes simplex virus resistant to acyclovir. A study in a tertiary care center
11. Acyclovir-resistant herpes simplex virus infections in patients with the acquired immunodeficiency syndrome
12. Recurrence and resistance of herpes simplex virus following cessation of > or = 6 years of chronic suppression with acyclovir
13. Susceptibility to acyclovir of herpes simplex virus: Emergence of resistance in patients with lymphoid and myeloid neoplasia
14. Analysis of herpes simplex virus isolated from the genital lesions since 1977 in Japan
15. Prolonged continuous acyclovir treatment of normal adults with frequently recurring genital herpes simplex virus infection
16. Molecular mechanisms of antiviral resistance
17. Administration of oral acyclovir suppressuve therapy after neonateal herpes simplex virus disease limited to the skin, eye and mouth: Results of a Phase I/II trial
18. Long-term suppression of severe recurrent genital herpes simplex infections with oral acyclovir: A dose-titration study
19. Antiviral traditional medicines against herpes simplex virus (HSV-1), poliovirus, and measles virus in vitro and their therapeutic efficacies for HSV-1 infection in mice
20. Purification and characterization of eugeniin as an anti-herpes virus compound from Geum japonicum and syzygium aromaticum
21. Recurrent genital herpes and suppressive oral acyclovir therapy. Relation between clinical outcome and in-vitro drug sensitivity
22. Extended acyclovir therapy for herpes genitalis: Changes in virus sensitivity and strain variation
23. Long-term acyclovir suppression of frequently recurring genital herpes simplex virus infection. A multicenter double-blind trial
24. One year acyclovir suppression of frequently recurring genital herpes: A study of efficacy, safety, virus sensitivity and antibody response
25. Suppression of recurrent genital herpes by single daily dosages of acyclovir
26. Herpes simplex virus variants resistant to high concentrations of acyclovir exist in clinical isolates
27. Homopolymer mutational hot spot mediate herpes simplex virus resistance to acyclovir
28. Suppression of frequently recurring genital herpes. A placebo-controlled double-blind trial of oral acyclovir
29. Acyclovir suppression of frequently recurring genital herpes efficacy and diminishing need during successive years of treatment
30. Chronic vulvar ulceration in an immunocompetent women due to acyclovir-resistant, thymidine kinase-deficient herpes simplex virus
31. Frequent genital herpes simplex virus 2 shedding in immunocompetent women. Effect of acyclovir treatment