Blood-brain barrier genomics

Journal of Cerebral Blood Flow and Metabolism

Volumn 21, Issue 1, 2001, Pages 61-68

  Li, J Y ^a   Boado, R J ^a   Pardridge, W M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Biologic transport; Blood brain barrier; Endothelium; Gene expression; Transferrin receptor

Indexed keywords

COMPLEMENTARY DNA; CONNEXIN 45; GENE PRODUCT; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MESSENGER RNA; MYELIN BASIC PROTEIN; RGS PROTEIN; SOMATOMEDIN B; TISSUE PLASMINOGEN ACTIVATOR; TRANSCRIPTION FACTOR; TRANSFERRIN RECEPTOR; UTROPHIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANION TRANSPORT; ARTICLE; BLOOD BRAIN BARRIER; BRAIN BLOOD VESSEL; BRAIN CAPILLARY; CONTROLLED STUDY; DATA BASE; DNA HYBRIDIZATION; DRUG DELIVERY SYSTEM; EXPRESSED SEQUENCE TAG; GENE EXPRESSION; GENE SEQUENCE; GENOME; KIDNEY; LIVER; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RAT; TISSUE SPECIFICITY; VASCULAR ENDOTHELIUM;

EID: 0035196665     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004647-200101000-00008     Document Type: Article

References (27)

1. Identification of a novel gene family encoding human liver-specific organic anion transporter LST-1
2. Pathology of multiple sclerosis: Progression of the lesion
3. Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence
4. A one-step procedure for isolation of poly A+ mRNA from isolated brain capillaries and endothelial cells in culture
5. Selective expression of the large neutral amino acid transporter (LAT) at the blood-brain barrier
6. A pilot trial of COP1 in exacerbating-remitting multiple sclerosis
7. Assessment with the electron-microscope of the permeability to peroxidase of cerebral endothelium and epithelium in mice and sharks
8. The membrane association domain of RGS16 contains unique amphipathic features that are conserved in RGS4 and RGS5
9. Suppression subtractive hybridization: A method for generating differentially regulated or tissue-specific cDNA probes and libraries
10. Utrophin transcription is activated by an intronic enhancer
11. Insulin-like growth factor II messenger ribonucleic acids are synthesized in the choroid plexus of the rat brain
12. Binding sites for vascular endothelial growth factor are localized on endothelial cells in adult rat tissues
13. Molecular cloning of transferrin receptor 2
14. Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction
15. Tissue distribution of insulin-like growth factor I and II messenger ribonucleic acid in the adult rat
16. Effects of circulating tumor necrosis factor on the neuronal activity and expression of the genes encoding the tumor necrosis factor receptors (p55 and p75) in the rat brain: A view from the blood-brain barrier
17. Isolation of a multispecific organic anion and cardiac glycoside transporter from rat brain
18. Human brain microvascular DR antigen
19. CNS drug design based on principles of bloodbrain barrier transport
20. Quantitative monitoring of gene expression patterns with a complementary DNA microarray
21. Endothelial caveolae have the molecular transport machinery for vesicle budding, docking, and fusion including VAMP, NSF, SNAP, annexins, and GPTases
22. Neuronal migration is retarded in mice lacking the tissue plasminogen activator gene
23. Biosynthesis of vascular endothelial growth factor-D involves proteolytic processing which generates non-covalent homodimers
24. Enhanced hepatic extraction of estrogens used for replacement therapy
25. RB and hbrm cooperate to repress the activation functions of E2F1
26. Use of suppression subtractive hybridization strategy for discovery of increased tissue inhibitor of matrix metalloproteinase-1 gene expression in brain ischemic tolerance
27. Detection of differentially expressed genes in primary tumor tissues using representational differences analysis coupled to microarray hybridization