Conditioning with high-dose cyclophosphamide may not be sufficient to provide a long-termn remission of paroxysmal nocturnal hemoglobinuria following syngeneic peripheral blood stem cell transplantation

Bone Marrow Transplantation

Volumn 28, Issue 10, 2001, Pages 987-988

  Cho, S G ^a   Lim, J ^a   Kim, Y ^a   Eom, H S ^a   Jin, C Y ^a   Han, C W ^a   Kim, C C ^a  

^a The Catholic University of Korea   (South Korea)

Author keywords

High dose cyclophosphamide; Paroxysmal nocturnal hemoglobinuria; Syngeneic peripheral blood stem cell transplantation

Indexed keywords

CYCLOPHOSPHAMIDE; GLYCOSYLPHOSPHATIDYLINOSITOL; LYMPHOCYTE ANTIBODY; PROTEIN; STEROID;

ADULT; ALLOGENIC BONE MARROW TRANSPLANTATION; ARTICLE; AUTOIMMUNE DISEASE; BLOOD TRANSFUSION; CASE REPORT; CELL CLONING; DRUG MEGADOSE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; IRON THERAPY; ISOGRAFT; LONG TERM CARE; MALE; PAROXYSMAL NOCTURNAL HEMOGLOBINURIA; PERIPHERAL BLOOD STEM CELL; PRIORITY JOURNAL; REMISSION;

ADULT; CYCLOPHOSPHAMIDE; FOLLOW-UP STUDIES; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMOGLOBINURIA, PAROXYSMAL; HUMANS; MALE; RECURRENCE; REMISSION INDUCTION; TRANSPLANTATION CONDITIONING; TRANSPLANTATION, ISOGENEIC; TREATMENT OUTCOME;

EID: 0035194794     PISSN: 02683369     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bmt.1703259     Document Type: Article

References (10)

1. Marrow transplantation for paroxysmal nocturnal hemoglobinuria
2. Myeloablative conditioning for marrow transplantation in myelodysplastic syndromes and paroxysmal nocturnal hemoglobinuria
3. Cure of aplastic anemia in paroxysmal nocturnal hemoglobinuria by bone marrow infusion from identical twin: Failure of peripheral-leukocyte transfusion to correct marrow aplasia
4. Bone marrow transplantation from identical twins in the treatment of aplastic anemia implications for the pathogenesis of the disease
5. Syngeneic bone marrow transplantation without conditioning in a patient with paroxysmal nocturnal hemoglobinuria: In vivo evidence that the mutant stem cells have a survival advantage
6. Long-term survival after marrow transplantation for paroxysmal nocturnal hemoglobinuria with aplastic anemia
7. Complete remission in severe aplastic anemia after high-dose cyclophosphamide without bone marrow transplantation
8. Somatic mutations in paroxysmal nocturnal hemoglobinuria: A blessing in disguise?
9. New somatic mutation in the PIG-A gene emerges at relapse of paroxysmal nocturnal hemoglobinuria
10. Bone marrow transplantation for paroxysmal nocturnal hemoglobinuria: Eradication of the PNH clone and documentation of complete lymphohematopoietic engraftment