A unique heparin-binding domain in the envelope protein of the neuropathogenic PVC-211 murine leukemia virus may contribute to its brain capillary endothelial cell tropism

Journal of Virology

Volumn 75, Issue 24, 2001, Pages 12439-12445

  Jinno Oue, A ^a   Oue, M ^a   Ruscetti, S K ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACE RECEPTOR; HEPARIN; HEPARIN BINDING PROTEIN; MEMBRANE PROTEIN; VIRUS ENVELOPE PROTEIN;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BRAIN CAPILLARY; CELL GROWTH; ENDOTHELIUM CELL; MURINE LEUKEMIA VIRUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; RAT; SULFATION; VIRUS INFECTION;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; BRAIN; CAPILLARIES; ENDOTHELIUM, VASCULAR; HEPARIN; LEUKEMIA VIRUS, MURINE; MOLECULAR SEQUENCE DATA; RATS; VIRAL ENVELOPE PROTEINS;

EID: 0035194421     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.75.24.12439-12445.2001     Document Type: Article

References (30)

1. A putative murine ecotropic retrovirus receptor gene encodes a multiple membrane-spanning protein and confers susceptibility to virus infection
2. Activity of dextran sulfate and other polysaccharides against human immunodeficiency virus
3. Importance of specific amino acids in protein binding sites for heparin and heparan sulfate
4. Molecular modeling of protein-glycosaminoglycan interactions
5. Localization of anticoagulantly active heparan sulfate proteoglycans in vascular endothelium: Antithrombin binding on cultured endothelial cells and perfused rat aorta
6. Structure of a murine leukemia virus receptor-binding glycoprotein at 2.0 Å resolution
7. Binding of heparin on the surface of cultured human endothelial cells
8. Endothelial negative surface charge areas and blood-brain barrier function
9. Glycosaminoglycan-protein interactions: Definition of consensus sites in glycosaminoglycan binding proteins
10. Cellular tropism and localization in the rodent nervous system of a neuropathogenic variant of Friend murine leukemia virus
11. Differential inhibitory effects of sulfated polysaccharides and polymers on the replication of various myxoviruses and retroviruses, depending on the composition of the target amino acid sequences of the viral envelope glycoproteins
12. Isolation of paralysis-inducing murine leukemia viruses from Friend virus passaged in rats
13. Isolation and characterization of heparan sulfate proteoglycans produced by cloned rat microvascular endothelial cells
14. Differential inhibition of retrovirus transduction by proteoglycans and free glycosaminoglycans
15. S-tropic murine type-C viruses: Frequency of isolation from continuous cell lines, leukemia virus preparations and normal spleens
16. Heparin binding, internalization, and metabolism in vascular smooth muscle cells. I. Upregulation of heparin binding correlates with antiproliferative activity
17. Heparin like molecules with anticoagulant activity are synthesized by cultured endothelial cells
18. Molecular characterization of a neuropathogenic and nonerythroleukemic variant of Friend murine leukemia virus PVC-211
19. Viral determinants that control neuropathogenicity of PVC-211 murine leukemia virus in vivo determine brain capillary endothelial cell tropism of the virus in vitro
20. Effect of subtle changes in the SU protein of ecotropic murine leukemia virus on its brain capillary endothelial cell tropism and interference properties
21. Capillary endothelial cell tropism of PVC-211 murine leukemia virus and its application for gene transduction
22. Identification of a heparin-binding protein using monoclonal antibodies that block heparin binding to porcine aortic endothelial cells
23. Interaction of heparin and antithrombin III. The role of O-sulfate groups
24. Initial binding of murine leukemia virus particles to cells does not require specific Env-receptor interaction
25. Total synthesis of heparin pentasaccharide fragment having high affinity for antithrombin III
26. Focus formation by murine sarcoma virus: Enhancement by DEAE-dextran
27. The entire nucleotide sequence of Friend-related and paralysis-inducing PVC-441 murine leukemia virus (MuLV) and its comparison with those of PVC-211 MuLV and Friend MuLV
28. Enhancement and inhibition of avian sarcoma viruses by polycations and polyanions
29. Ultracytochemical characterization of anionic sites in the wall of brain capillaries