Effects of ceronapril alone or in combination with alcohol on psychomotor performance in healthy volunteers: A placebo-controlled, crossover study

Current Therapeutic Research - Clinical and Experimental

Volumn 62, Issue 10, 2001, Pages 699-708

  Vanakoski, Jyrki ^a,b   Seppälä, Timo ^a,d   Strömberg, Christer ^b   Näveri, Liisa ^b   Hammett, Janis ^c   Ford, Neville ^c  

^a UNIVERSITY OF HELSINKI   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

^c BRISTOL MYERS SQUIBB PHARMACEUTICAL RESEARCH INSTITUTE   (United States)

^d NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

Author keywords

Ceronapril; Ethanol; Interaction; Lorazepam

Indexed keywords

ALCOHOL; ANXIOLYTIC AGENT; CERANAPRIL; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; LORAZEPAM; PLACEBO;

ADULT; ALCOHOL CONSUMPTION; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DRUG TOLERANCE; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; PRIORITY JOURNAL; PSYCHOMOTOR PERFORMANCE; RANDOMIZED CONTROLLED TRIAL; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SEDATION; TASK PERFORMANCE; TRANQUILIZING ACTIVITY;

EID: 0035192756     PISSN: 0011393X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0011-393X(01)80077-1     Document Type: Article

References (20)

1. The effects of ACE inhibitors captopril and SQ 29,852 in rodent tests of cognition
2. Angiotensin-converting enzyme inhibition, angiotensin, and cognition
3. A pilot clinical trial of the angiotensin-converting enzyme inhibitor ceronapril in Alzheimer disease
4. The reduction in alcohol intake produced by enalapril is not attenuated by centrally administered angiotensin inhibitors
5. Effects of angiotensin II and an angiotensin converting enzyme inhibitor on alcohol intake in P and NP rats
6. Lorazepam: A review of its clinical pharmacological properties and therapeutic uses
7. Interaction of diazepam or lorazepam with alcohol. Psychomotor effects and bioassayed serum levels after single and repeated doses
8. Lorazepam and diazepam differently impair divided attention
9. A new device to measure drug-related changes on reactive and coordinative skills of human performance
10. Critical flicker frequency (CFF) and psychotropic drugs in normal human subjects - A review
11. Standardization in platform stabilometry being a part of posturography
12. Measurement of recovery from outpatient general anaesthesia with a simple ocular test
13. Single oral doses of amisulpride do not enhance the effects of alcohol on the performance and memory of healthy subjects
14. "Mini-mental state": A practical method for grading the cognitive state of patients for the clinician
15. The use of visual analogue scales in rating subjective feelings
16. Über die gaschromatographische blutalkoholbestimmung
17. Drugs, alcohol and driving
18. Angiotensin II receptors and angiotensin II receptor antagonists
19. 3H] ceronapril recognition sites in rat and human brain tissue
20. Angiotensin converting enzyme density is increased in temporal cortex from patients with Alzheimer's disease