Modification of sodium transport and alveolar fluid clearance by hypoxia: Mechanisms and physiological implications

American Journal of Respiratory Cell and Molecular Biology

Volumn 25, Issue 5, 2001, Pages 538-541

  Hardiman, K M ^a   Matalon, S ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0035191971     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/ajrcmb.25.5.f219     Document Type: Review

References (33)

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2. Early death due to defective neonatal lung liquid clearance in αENaC-deficient mice
3. Salt and water transport across alveolar and distal airway epithelia in the adult lung
4. Mechanisms and sequelae of increased alveolar fluid clearance in hyperoxic rats
5. Augmentation of lung liquid clearance via adenovirus-mediated transfer of a Na,K-ATPase beta1 subunit gene
6. Intact epithelial barrier function is critical for the resolution of alveolar edema in humans
7. Alveolar fluid clearance is impaired in the majority of patients with acute lung injury and the acute respiratory distress syndrome
8. Increased expression and activity of sodium channels in alveolar type II cells of hyperoxic rats
9. Antisense oligonucleotides against the alpha-subunit of ENaC decrease lung epithelial cation-channel activity
10. --ATPase function in A549 cells
11. cAMP activation of chloride and fluid secretion across the rabbit alveolar epithelium
12. Adrenergic stimulation of Na+ transport across alveolar epithelial cells involves activation of apical Cl- channels
13. Quantitation and localization of ENaC subunit expression in fetal, newborn, and adult mouse lung
14. Sodium channels in alveolar epithelial cells: Molecular characterization, biophysical properties, and physiological significance
15. High-altitude pulmonary edema: From exaggerated pulmonary hypertension to a defect in transepithelial sodium transport
16. Hypoxia reduces alveolar epithelial sodium and fluid transport in rats: Reversal by β-adrenergic agonist treatment
17. Differential liquid and protein clearance from the alveoli of anesthetized sheep
18. Alterations in adenosine triphosphate and energy charge in cultured endothelial and P388D1 cells after oxidant injury
19. Relationship of interstitial fluid volume to alveolar fluid clearance in mice: Ventilated vs. in situ studies
20. Lack of amiloridesensitive transport across alveolar and respiratory epithelium of iNOS(-/-) mice in vivo
21. Tight monolayers of rat alveolar epithelial cells: Bioelectric properties and active sodium transport
22. Biophysical properties and molecular characterization of amiloride-sensitive sodium channels in A549 cells
23. ANF decreases active sodium transport and increases alveolar epithelial permeability in rats
24. Significant levels of oxidants are generated by isolated cardiomyocytes during ischemia prior to reperfusion
25. Impairment of transalveolar fluid transport and lung Na(+)-K(+)-ATPase function by hypoxia in rats
26. Biosynthesis and processing of epithelial sodium channels in Xenopus oocytes
27. Isoproterenol increases Na+-K+-ATPase activity by membrane insertion of alpha-subunits in lung alveolar cells
28. β-Adrenergic stimulation restores rat lung ability to clear edema in ventilator-associated lung injury
29. Regulation of low-amiloride-affinity sodium channels in alveolar type II cells
30. Inhibition of Na-K-ATPase activity after prolonged hypoxia in an alveolar epithelial cell line
31. Impairment of cation transport in A549 cells and rat alveolar epithelial cells by hypoxia
32. Hypoxia downregulates expression and activity of epithelial sodium channels in rat alveolar epithelial cells
33. Hypoxia decreases proteins involved in epithelial electrolyte transport in A549 cells and rat lung