A 1-year comparison of the efficacy and clinical tolerance in postmenopausal women of two hormone replacement therapies containing estradiol in combination with either norgestrel or trimegestone

Gynecological Endocrinology

Volumn 15, Issue 5, 2001, Pages 349-358

  Spielmann, D ^a   Meuwissen, J H J M ^b   De Villiers, T J ^c   Beijers De Bie, L ^b   Vihtamaki, T ^d   Tuimala, R ^d   Siseles, N ^e   Magaril, C ^f   The, H S ^g   Houben, P W H ^g   Murga, M ^h  

^a Wyeth Ayerst   (France)

^b Diagnostisch Centrum Eindhoven   (Netherlands)

^c Panorama Medi Clinic   (South Africa)

^d Koskiklinikka   (Finland)

^e HOSPITAL FRANCÉS   (Argentina)

^f HOSPITAL RAMOS MEJÍA   (Argentina)

^g Location Alkmaar   (Netherlands)

^h Hospital Bernardino Rivadavia   (Argentina)

Author keywords

Clinical tolerance; Efficacy; Estradiol; Hormone replacement therapy; Norgestrel; Trimegestone

Indexed keywords

ESTRADIOL; ESTRADIOL PLUS TRIMEGESTONE; ESTRADIOL VALERATE PLUS NORGESTREL; TRIMEGESTONE; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CLIMACTERIUM; CLINICAL FEATURE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE SEVERITY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG FORMULATION; DRUG TOLERABILITY; DRUG WITHDRAWAL; ENDOMETRIUM HYPERPLASIA; FEMALE; HORMONE SUBSTITUTION; HOT FLUSH; HUMAN; MAJOR CLINICAL STUDY; MASTALGIA; MULTICENTER STUDY; POSTMENOPAUSE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; UTERUS BLEEDING;

EID: 0035191789     PISSN: 09513590     EISSN: None     Source Type: Journal    
DOI: 10.1080/713602926     Document Type: Article

References (9)

1. Symptoms of oestrogen deficiency
2. The effect of estrogen deficiency on the bladder
3. The clinical problem of treating osteoporosis with estrogens
4. The cardioprotective effects of estrogens
5. The pharmacological profile of a novel norpregnane progestin (trimegestone)
6. Effects of 17β-estradiol and trimegestone alone, and in combination, on the bone and uterus of ovariectomized rats
7. Endometrial effects of three doses of trimegestone, a new orally active progestogen, on the postmenopausal endometrium
8. Acceptability and patterns of endometrial bleeding in estradiol-based HRT regimens: A comparative study of cyclical sequential combinations of trimegestone or norethisterone acetate
9. Comparative clinical evaluation of estrogenic preparations by the menopausal and amenorrheal indices