Hormonal regulation of male-specific 20β-hydroxysteroid dehydrogenase with carbonyl reductase-like activity present in kidney microsomes of rats

Journal of Steroid Biochemistry and Molecular Biology

Volumn 78, Issue 4, 2001, Pages 373-378

  Imamura, Yorishige ^a   Takada, Hidenori ^a   Kamizono, Rika ^a   Otagiri, Masaki ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

Author keywords

Androgen dependent regulation; Carbonyl reductase like activity; Male specific 20 hydroxysteroid dehydrogenase; Rat kidney microsomes

Indexed keywords

20 BETA HYDROXYSTEROID DEHYDROGENASE; 20ALPHA HYDROXYSTEROID DEHYDROGENASE; ACETOHEXAMIDE; ACETOHEXAMIDE REDUCTASE; CARBONYL REDUCTASE; CORTISONE; HYDROCORTISONE; HYDROXYPROGESTERONE; KETONE; OXIDOREDUCTASE; PROGESTERONE; STEROID; STEROID REDUCTASE; TESTOSTERONE PROPIONATE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; COMPETITIVE INHIBITION; CONTROLLED STUDY; DRUG ACTIVITY; ENZYME ACTIVITY; FEMALE; HORMONAL REGULATION; HORMONE STRUCTURE; HYPOPHYSECTOMY; KIDNEY MICROSOME; MALE; NONHUMAN; ORCHIECTOMY; OVARIECTOMY; RAT; REDUCTION; SEX DIFFERENCE;

ALCOHOL OXIDOREDUCTASES; ANIMALS; CORTISONE REDUCTASE; FEMALE; KIDNEY; MALE; MICROSOMES; ORCHIECTOMY; PITUITARY GLAND; RATS; RATS, INBRED F344; SEX FACTORS; SUBSTRATE SPECIFICITY;

EID: 0035185849     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-0760(01)00110-8     Document Type: Article

References (27)

1. The enzymes of detoxication
2. Xenobiotic carbonyl reduction and physiological steroid oxidoreduction: The pluripotency of several hydroxysteroid dehydrogenases
3. The nomenclature of aldehyde reductases
4. Human carbonyl reductase: Nucleotide sequence analysis of a cDNA and amino acid sequence of the encoded protein
5. Cloning and sequence analysis of a cDNA encoding tetrameric carbonyl reductase of pig lung
6. Short-chain dehydrogenase/reductase (SDR)
7. Carbonyl reductase purified from rabbit liver is not the product of a carbonyl reductase gene (RCBR5 or RCBR6) cloned from the rabbit liver cDNA library
8. 113-Hydroxysteroid dehydrogenase mediates reductive metabolism of xenobiotic carbonyl compounds
9. Metabolism of pravastatin sodium by 3α-hydroxysteroid dehydrogenase
10. Cloning and primary structure of murine 11β-hydroxysteroid dehydrogenase/microsomal carbonyl reductase
11. The 11β-hydroxysteroid dehydrogenase system, a determinant of glucocorticoid and mineralocorticoid action: Role of type-1 11β-hydroxysteroid dehydrogenase in detoxification processes
12. Pig testicular 20β-hydroxysteroid dehydrogenase exhibits carbonyl reductase-like structure and activity: cDNA cloning of pig testicular 20β-hydroxysteroid dehydrogenase
13. Carbonyl reductase activity exhibited by pig testicular 20β-hydroxysteroid dehydrogenase
14. 20β-Hydroxysteroid dehydrogenase catalyzes ketone-reduction of acetohexamide, an oral antidiabetic drug, in liver microsomes of adult male rats
15. Further studies on 20β-hydroxysteroid dehydrogenase with carbonyl reductase-like activity present in liver microsomes of male rats
16. Postnatal development, sex-related difference and hormonal regulation of acetohexamide reductase activities in liver and kidney
17. Fluorometric determination of acetohexamide in plasma and tablet formulation using 1-methyl-nicotinamide
18. High-performance liquid chromatographic determination of acetohexamide and its metabolite hydroxyhexamide
19. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
20. Regioselective progesterone hydroxylation catalyzed by Elever rat hepatic cytochrome P-450 isozymes
21. Metabolic reduction of acetohexamide in rat kidney: Sex difference and effect of strepto-zotocin-induced diabetes
22. Factors affecting acetohexamide reductase activities in microsomes and cytosol from the kidney of male rats: Age and castration
23. Hormonal regulation of cytochrome P-450 in rat liver
24. Zonation of hepatic cytochrome P-450 expression and regulation
25. Hormonal regulation of microsomal cytochrome P-450 2C11 in rat liver and kidney
26. Continuous infusion of growth hormone feminizes hepatic steroid metabolism in the rat
27. The effects of pituitary hormones on hepatic drug metabolism in the rat