Mitogen-activated protein kinase activity regulation role of angiotensin and endothelin systems in vascular smooth muscle cells

European Journal of Pharmacology

Volumn 411, Issue 1-2, 2001, Pages 27-34

  Kubo, Takao ^a   Ibusuki, Takahiro ^a   Chiba, Satosi ^a   Kambe, Toshie ^a   Fukumori, Ryuji ^a  

^a SHOWA PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Angiotensin; Endothelin 1; MAP (mitogen activated protein kinase); Renin; Smooth muscle cells

Indexed keywords

ANGIOTENSIN I; ANGIOTENSIN RECEPTOR ANTAGONIST; BIG ENDOTHELIN 1; CAPTOPRIL; CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL); DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENDOTHELIN 1; ENDOTHELIN CONVERTING ENZYME INHIBITOR; ENDOTHELIN RECEPTOR ANTAGONIST; LOSARTAN; MITOGEN ACTIVATED PROTEIN KINASE; PEPSTATIN; PHOSPHORAMIDON; RENIN INHIBITOR;

ANIMAL TISSUE; ARTICLE; CELL CULTURE; CONCENTRATION RESPONSE; CONNECTIVE TISSUE; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; ENZYME REGULATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; VASCULAR SMOOTH MUSCLE;

ANGIOTENSIN I; ANGIOTENSIN II; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANIMALS; CAPTOPRIL; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIN-1; ENDOTHELINS; GLYCOPEPTIDES; LOSARTAN; MALE; MITOGEN-ACTIVATED PROTEIN KINASES; MUSCLE, SMOOTH, VASCULAR; PEPSTATINS; PEPTIDES, CYCLIC; PROTEASE INHIBITORS; PROTEIN PRECURSORS; RATS; RATS, WISTAR; RECEPTORS, ENDOTHELIN; RENIN;

EID: 0035184930     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(00)00857-8     Document Type: Article

References (31)

1. Pro-Leu-Ser/Thr-Pro is a consensus primary sequence for substrate protein phosphorylation: Characterization of the phosphorylation of c-myc and c-jun proteins by an epidermal growth factor receptor threonine 669 protein kinase
2. The role of the renin-angiotensin system in cardiovascular disease
3. Angiotensinogen gene is expressed and differentially regulated in multiple tissues of the rat
4. Location and regulation of rat angiotensinogen messenger RNA
5. A role for endogenous endothelin-1 in neointimal formation following rat carotid artery balloon angioplasty: Protective effects of the non-peptide endothelin receptor antagonist SB 209670
6. Angiotensin II stimulates the pp44 and pp42 mitogen-activated protein kinases in cultured rat aortic smooth muscle cells
7. Cell biology of vascular hypertrophy in systemic hypertension
8. Extra-renal transcription of the renin genes in multiple tissues of mice and rats
9. Glucocorticoids induce angiotensin-converting enzyme expression in vascular smooth muscle
10. Importance of adaptive changes in vascular design for establishment of primary hypertension studied in man and in spontaneously hypertensive rats
11. Polymerase chain reaction analysis of renin in rat aortic smooth muscle
12. Pharmacology of smooth muscle cell replication
13. Endothelin-1 stimulates tyrosine phosphorylation and the activities of two mitogen-activated protein kinases in cultured vascular smooth muscle cells
14. Xenopus MAP kinase activator is a serine/threonine/tyrosine kinase activated by threonine phosphorylation
15. Cardiovascular reactivity in renal and spontaneously hypertensive rats
16. Evidence that angiotensin II, endothelins and nitric oxide regulate mitogen-activated protein kinase activity in rat aorta
17. Local renin-angiotensin system and mitogen-activated protein kinase activation in rat aorta
18. Protein measurement with the Folin phenol reagent
19. Angiotensin II stimulation of rapid protein tyrosine phosphorylation and protein kinase activation in rat aortic smooth muscle cells
20. Localization and differential regulation of angiotensinogen mRNA expression in the vessel wall
21. Alterations in vascular smooth muscle mass in the spontaneously hypertensive rat: Role of cellular hypertrophy, hyperploidy, and hyperplasia
22. Endothelium removal does not abolish angiotensin converting enzyme activity from the mesenteric arterial bed of the rat
23. Inhibitors of angiotensin-converting enzyme prevent myointimal proliferation after vascular injury
24. Phosphorylation of c-jun mediated by MAP kinases
25. Renin synthesis by canine aortic smooth muscle cells in culture
26. The smooth muscle. II. Growth of smooth muscle in culture and formation of elastic fibers
27. Expression of the renin gene in extra-renal tissues of the rat
28. Hypertension-induced changes of platelet-derived growth factor receptor expression in rat aorta and heart
29. Insulin-stimulated MAP-2 kinase phosphorylates and activates ribosomal protein S6 kinase II
30. Angiotensin type 1 receptors mediate smooth muscle proliferation and endothelin biosynthesis in rat vascular smooth muscle
31. Angiotensin II stimulates two myelin basic protein/microtubule-associated protein 2 kinases in cultured vascular smooth muscle cells