Thin-layer chromatographic characterization of metabolites formed from an AMPA antagonist drug candidate

Journal of Planar Chromatography - Modern TLC

Volumn 14, Issue 4, 2001, Pages 266-271

  Migleczi K ^a   Hazai, I ^a   Jemnitz, K ^a   Patfalusi M ^a  

^a Institute for Drug Research Budapest   (Hungary)

Author keywords

2,3 benzodiazepine; AMPA antagonist; Metabolic profiles; N acetylation; Radio TLC

Indexed keywords

ACETYLATION; AMINO ACIDS; MASS SPECTROMETRY; METABOLITES;

ANTAGONIST DRUG;

THIN LAYER CHROMATOGRAPHY;

2 AMINO 3 (3 HYDROXYMETHYLISOXAZOL 4 YL)PROPIONIC ACID; 6 (4 AMINOPHENYL) 8 CHLORO 2 METHYL 11H IMIDAZO [1,2C] [2,3] BENZODIAZEPINE; AMPA RECEPTOR ANTAGONIST; DRUG METABOLITE; UNCLASSIFIED DRUG;

ACETYLATION; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOG; DRUG METABOLISM; DRUG STRUCTURE; IN VITRO STUDY; IN VIVO STUDY; ISOTOPE LABELING; LIVER CELL; MASS SPECTROMETRY; MOUSE; NONHUMAN; PILOT STUDY; RABBIT; RAT; SAMPLE; SPECIES; THIN LAYER CHROMATOGRAPHY;

EID: 0035182549     PISSN: 09334173     EISSN: None     Source Type: Journal    
DOI: 10.1556/JPC.14.2001.4.8     Document Type: Article

References (6)

1. Application of Planar Chromatography and Digital Autoradiography in Metabolism Research'
2. Acetylation