Biochemical properties of a newly synthesized H+/K+ ATPase inhibitor, 1-(2-methyl-4-methoxyphenyl)-4-[(3-hydroxypropyl)amino]-6-methyl-2,3-dihyd ropyrrolo[3,2-c]quinoline

European Journal of Pharmacology

Volumn 411, Issue 1-2, 2001, Pages 181-186

  Cheon, Hyae Gyeong ^a   Lim, Hong ^b   Lee, Dong Ha ^b  

^a Korea Research Institute of Chemical Technology   (South Korea)

^b Dongbu Hannong Chemical Co   (South Korea)

Author keywords

Acid activation; H+ K+ ATPase; Non competitive inhibition; Reversibility

Indexed keywords

2,3 DIHYDRO 4 (3 HYDROXYPROPYLAMINO) 1 (4 METHOXY 2 METHYLPHENYL) 6 METHYLPYRROLO[3,2 C]QUINOLINE; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM) INHIBITOR; PROTON PUMP INHIBITOR; UNCLASSIFIED DRUG;

ACIDITY; ARTICLE; COMPETITIVE INHIBITION; CONTROLLED STUDY; DOG; DRUG POTENCY; DRUG SELECTIVITY; ENZYME INACTIVATION; ENZYME INHIBITION; NONHUMAN; PEPTIC ULCER; PRIORITY JOURNAL; RABBIT;

ACIDS; ANIMALS; DITHIOTHREITOL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; GASTRIC MUCOSA; H(+)-K(+)-EXCHANGING ATPASE; HYDROGEN-ION CONCENTRATION; KINETICS; OMEPRAZOLE; PYRROLES; QUINOLINES; RABBITS;

EID: 0035179422     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(00)00919-5     Document Type: Article

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