Serotonin elicits long-lasting enhancement of rhythmic respiratory activity in turtle brain stems in vitro

Journal of Applied Physiology

Volumn 91, Issue 6, 2001, Pages 2703-2712

  Johnson, Stephen M ^a   Wilkerson, Julia E R ^a   Henderson, Daniel R ^a   Wenninger, Michael R ^a   Mitchell, Gordon S ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

5 Hydroxytryptamine; Control of breathing; Plasticity; Reptile; Respiratory control; Rhythm generation

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; 4 (4 METHYL 1 PIPERAZINYL) 7 TRIFLUOROMETHYLPYRROLO[1,2 A]QUINOXALINE; METITEPINE; PHENYLBIGUANIDE; SEROTONIN; SEROTONIN 1A AGONIST; SEROTONIN 1B AGONIST; SEROTONIN 3 AGONIST; SEROTONIN 3 ANTAGONIST; SEROTONIN 3 RECEPTOR; SEROTONIN ANTAGONIST; TROPESITRON; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN STEM; BREATHING PATTERN; BREATHING RATE; CONTROLLED STUDY; DOSE RESPONSE; HYPOGLOSSAL NERVE; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; RESPIRATION CONTROL; RHYTHM; TURTLE;

EID: 0035178971     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/jappl.2001.91.6.2703     Document Type: Article

References (49)

1. Serotonergic and noradrenergic effects on respiratory neural discharge in the medullary slice preparation of neonatal rats
2. The influence of increased brain 5-hydroxytryptamine upon the respiratory activity of cats
3. Respiratory network function in the isolated brainstem-spinal cord of newborn rats
4. Inhibition of N- and P-type calcium currents and the afterhyperpolarization in rat motoneurones by serotonin
5. Neuromodulation of hypoglossal motoneurons: Cellular and developmental mechanisms
6. Modulation of neonatal rat hypoglossal motoneuron excitability by serotonin
7. Central control of breathing in mammals: Neuronal circuitry, membrane properties, and neurotransmitters
8. Neurotransmitters in the CNS control of breathing
9. Brain ECF and central chemical control of ventilation during anoxia in turtles
10. Serotonergic modulation of the respiratory rhythm generator at birth: An in vitro study in the rat
11. Episodic respiratory related discharge in turtle cranial motoneurons: In vivo and in vitro studies
12. Long term facilitation of phrenic motor output
13. Short-term modulation of the exercise ventilatory response in goats: Effects of 8-OH-DPAT and MPPI
14. Maturation of the mammalian respiratory system
15. Changes in serotonin metabolism may elicit obstructive apnoea in the newborn rat
16. International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (serotonin)
17. Structure and function of the brain serotonin system
18. Constant and episodic 5-HT exposuresm produce different effects in respiratory discharge of isolated turtle brainstems
19. 2 effects on respiratory discharge from a turtle brain stem preparation
20. CO2-insensitive in turtle brainstem-spinal cord preparation
21. i/o protein-mediated mechanisms
22. Central effects of 5-HT on activity of respiratory and hypoglossally innervated muscles in newborn kittens
23. Central effects of 5-HT on respiratory rhythm in newborn rats in vivo
24. Monoaminergic systems in the brainstem and spinal cord of the turtle Pseudemys scripta elegans as revealed by antibodies against serotonin and tyrosine hydroxylase
25. Serotonergic excitatory drive to hypoglossal motoneurons in the decerebrate rat
26. Nucleus raphe obscurus evokes 5-HT-1A receptor-mediated modulation of respiratory neurons
27. An evaluation of the mechanism by which serotonergic activation depresses respiration
28. Further evidence that various 5-HT receptor subtypes modulate central respiratory activity: In vitro studies with SR 46349B
29. Differential effects of serotonin on respiratory activity of hypoglossal and cervical motoneurons: An in vitro study on the newborn rat
30. 3 receptor subtype in the rat brain and spinal cord
31. Compared effects of serotonin on the inspiratory activity of glossopharyngeal, vagal, hypoglossal and cervical motoneurons in neonatal rat brain stem-spinal cord preparations
32. Serotonergic influences on central respiratory activity: An in vitro study in the newborn rat
33. Depressant effect of raphe stimulation on inspiratory activity of the hypoglossal nerve: In vitro study in the newborn rat
34. 5-Hydroxytryptamine modulates central respiratory activity in the newborn rat: An in vitro study
35. Compared effects of serotonin on cervical and hypoglossal inspiratory activities: An in vitro study in the newborn rat
36. 1 receptors in the control of hypoglossal motoneurons in vivo
37. Modulation of respiratory rhythm by 5-HT in the brainstem-spinal cord preparation from newborn rat
38. Time domains of the hypoxic ventilatory response
39. PreBötzinger complex and pacemaker neurons: Hypothesized site and kernel for respiratory rhythm generation
40. Hypoglossal and phrenic motoneuron responses to serotonergic active agents in rats
41. Neurotransmitters and neuromodulators controlling the hypoxic respiratory response in anesthetized cats
42. Central effects of 5-HT on respiratory and hypoglossal activities in the adult cat
43. Presynaptic inhibition of glutamatergic synaptic transmission to rat motoneurons by serotonin
44. Pre-Botzinger complex: A brainstem region that may generate respiratory rhythm in mammals
45. Postsynaptic potentials of bulbar respiratory neurons of the turtle
46. Postnatal development of serotonergic innervation, 5-HT1A receptor expression, and 5-HT responses in rat motoneuron
47. Presynaptic inhibition by serotonin of glycinergic inhibitory synaptic currents in the rat brain stem