Intramuscular rapacuronium in infants and children: A comparative multicenter study to confirm the efficacy and safety of the age-related tracheal intubating doses of intramuscular rapacuronium (ORG 9487) in two groups of pediatric subjects

Anesthesiology

Volumn 94, Issue 1, 2001, Pages 3-7

  Denman, William T ^a,f   Kaplan, Richard F ^b   Goudsouzian, Nishan G ^a   Uejima, Tetsu ^c   Barcelona, Sandra L ^c   Cote, Charles J ^d   Ginsberg, Brian ^e   Hannallah, Raafat S ^b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

^c Children's Hospital Medical Center   (United States)

^d CHILDREN'S MEMORIAL HOSPITAL   (United States)

^e DUKE UNIVERSITY MEDICAL CENTER   (United States)

^f TUFTS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HALOTHANE; RAPACURONIUM BROMIDE;

AGE; ARTICLE; BRONCHOSPASM; CHILD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG POTENCY; ENDOTRACHEAL INTUBATION; ERYTHEMA; FEMALE; HUMAN; INFANT; INHALATION ANESTHESIA; INJECTION SITE; MAJOR CLINICAL STUDY; MALE; MINIMUM LUNG ALVEOLUS CONCENTRATION; MULTICENTER STUDY; NEUROMUSCULAR BLOCKING; PEDIATRIC ANESTHESIA; PRESCHOOL CHILD; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SCHOOL CHILD; SINGLE BLIND PROCEDURE; SKIN EDEMA;

EID: 0035175201     PISSN: 00033022     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000542-200101000-00006     Document Type: Article

References (20)

1. Preliminary investigations of the clinical pharmacology of three short-acting non-depolarizing neuromuscular blocking agents, ORG 9453, ORG 9489, and ORG 9487
2. Time course and endotracheal intubating conditions of ORG 9487, a new short acting steroidal muscle relaxant, a comparison with succinylcholine
3. Comparison of intubating conditions after rapacuronium (ORG 9487) and succinylcholine following rapid sequence induction in adult patients
4. 50) and cardiovascular effects of rapacuronium (ORG 9487) during narcotic-nitrous oxide-propofol anesthesia in neonates, infants and children
5. Neuromuscular effects of rapacuronium in pediatric patients during nitrous oxide-halothane anesthesia: Comparison with mivacurium
6. A dose-ranging study of rapacuronium in pediatric patients
7. Dose response to intramuscular succinylcholine in children
8. Neuromuscular blockade in infants following intramuscular succinylcholine in two or five per cent concentration
9. Intramuscular rapacuronium in infants and children: Dose-ranging and tracheal intubating conditions
10. Pharmacokinetics of rapacuronium in infants and children with intravenous and intramuscular administration
11. Intramuscular rocuronium in infants and children: A multicenter study to evaluate tracheal intubating conditions, onset, and duration of action
12. Intramuscular rocuronium in infants and children: Dose-ranging and tracheal intubating conditions
13. Is intramuscular mivacurium an alternative to intramuscular succinylcholine?
14. Comparison of twitch depression of the adductor pollicis and the respiratory muscles: Pharmacodynamic modeling without plasma concentrations
15. Rocuronium (ORG 9426) neuromuscular blockade at the adductor muscles of the larynx and adductor pollicis in humans
16. Comparison of sevoflurane and halothane for outpatient dental anaesthesia in children
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18. Editorial II: Why we need large randomized studies in anaesthesia