Frequency-dependent electrophysiological effects of flecainide, nifekalant and d,l-sotalol on the human atrium

Japanese Circulation Journal

Volumn 65, Issue 1, 2001, Pages 1-6

  Watanabe, H ^a   Watanabe, I ^a   Nakai, T ^a   Oshikawa, N ^a   Kunimoto, S ^a   Masaki, R ^a   Kojima, T ^a   Saito, S ^a   Ozawa, Y ^a   Kanmatuse, K ^a  

^a NIHON UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Antiarrhythmic drugs; Atrial muscle; Monophasic action potential; Reverse use dependency; Use dependency

Indexed keywords

ANTIARRHYTHMIC AGENT; FLECAINIDE; NIFEKALANT; SOTALOL;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG INDICATION; HEART ATRIUM ARRHYTHMIA; HEART ATRIUM CONDUCTION; HEART ATRIUM FIBRILLATION; HEART ATRIUM FLUTTER; HEART ELECTROPHYSIOLOGY; HEART MUSCLE POTENTIAL; HEART MUSCLE REFRACTORY PERIOD; HUMAN; REENTRY TACHYCARDIA; SICK SINUS SYNDROME; WOLFF PARKINSON WHITE SYNDROME;

ACTION POTENTIALS; ADOLESCENT; ADULT; AGED; ANTI-ARRHYTHMIA AGENTS; ATRIAL FIBRILLATION; ATRIAL FUNCTION; COHORT STUDIES; DRUG EVALUATION; ELECTROPHYSIOLOGIC TECHNIQUES, CARDIAC; FLECAINIDE; HEART ATRIA; HUMANS; MIDDLE AGED; PYRIMIDINONES; SOTALOL;

EID: 0035173319     PISSN: 00471828     EISSN: None     Source Type: Journal    
DOI: 10.1253/jcj.65.1     Document Type: Article

References (29)

1. Mechansm of action of antiarrhythmic drugs
2. Electrophysiologic basis for the antiarrhythmic actions of sotalol and comparison with other agents
3. Class III antiarrhythmic agents have a lot of potential but a long way to go: Reduced effectiveness and dangers of reverse use dependence
4. Cycle length dependence of human action potential duration in vivo
5. Effects of flecainide on the electophysiologic properties of isolated canine and rabbit myocardial fibers
6. Flecainide: Unusual use-dependent kinetics
7. Arrhythmic and electro-physiologic actions of flecainide and animal models
8. Cellular electro-physiological effects of flecainide on human atrial fibers
9. Effect of flecainide, quinidine, and 4-aminopyridine on transient outward and ultrarapid delayed rectifier currents in human atrial myocyte
10. Block of delayed rectifier potassium current, Ik, by flecainide and E-4031 in cat ventricular myocyte
11. Effect of flecainide on atrial electrophysiology in the Wolff-Parkinson-White syndrome
12. Effect of flecainide on atrial and ventricular refractoriness and conduction in patients with normal left ventricle
13. Effects of flecainide on the rate dependence of atrial refractoriness, atrial repolarization and atrioventricular node conduction in anesthetized dogs
14. Electro-physiological effects of a new antiarrhythmic agent, flecainide, on the intact canine heart
15. Electrophysiological action of MS-551, a new antiarrhythmic agent, on ventricular myocyte
16. Effects of MS-551, a new class III antiarrhythmic drug, on action potential and membrane currents in rabbit ventricular myocyte
17. MS-551: Pharmacologial profile of a novel class III anti-arrhythmic agent
18. Effect of Na and K channel blockers on the spatial and temporal dispersion of atrial refractoriness during atrial fibrillation
19. Antiarrhythmic effects of MS-551, a new class III antiarrhythmic agent, on canine models of ventricular arrhythmia
20. Electrophysiological effect of a novel class III antiarrhythmic agent, MS-551 on human atrium and ventricle
21. Effect of MS-551 (class III) on electrically induced atrial flutter and atrial fibrillation in the dog
22. Reverse use dependence of human ventricular repolarization by chronic oral sotalol in monophasic action potential recordings
23. Prolongation of the human cardiac monophasic action potential by sotalol
24. Mechanism of atrial fibrillation - Clinical electrophysiological test for atrial vulnerability
25. β-adrenergic blocking drugs
26. Different effect of pharmacological autonomic blockade on some electrophysiological properties of the human ventricle and atrium
27. Post repolarization refractoriness as a potent anti-atrial fibrillation mechanism of pilsicainide, a pure sodium channel blocker with slow recovery kinetics
28. Post repolarization refractoriness as a potent anti-atrial fibrillation mechanism of pilsicainide, a pure sodium channel blocker with slow recovery kinetics
29. Frequency-dependent electrophysiological effects of nifekalant on human atrium in patients with chronic atrial fibrillation cardioverted with internal atrial defibrillation