Association of the Pro90Ser CD36 mutation with elevated free fatty acid concentrations but not with insulin resistance syndrome in Japanese

Clinica Chimica Acta

Volumn 314, Issue 1-2, 2001, Pages 125-130

  Kajihara, Susumu ^a   Hisatomi, Akitaka ^a   Ogawa, Yoko ^a   Yasutake, Tsutomu ^a   Yoshimura, Tohru ^a   Hara, Toshiya ^a   Mizuta, Toshihiko ^a   Ozaki, Iwata ^a   Iwamoto, Noriyuki ^a   Yamamoto, Kyosuke ^a  

^a SAGA UNIVERSITY   (Japan)

Author keywords

CD36; CD36 deficiency; FFA; Insulin resistance syndrome

Indexed keywords

CD36 ANTIGEN; GENE PRODUCT; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; PROLINE; SERINE; TRIACYLGLYCEROL; FATTY ACID; LIPID; LIPOPROTEIN;

ADULT; ARTICLE; BLOOD PRESSURE; BODY MASS; CHOLESTEROL BLOOD LEVEL; CONCENTRATION RESPONSE; CONTROLLED STUDY; FEMALE; GENE MUTATION; HETEROZYGOSITY; HETEROZYGOTE; HOMOZYGOSITY; HOMOZYGOTE; HUMAN; INSULIN RESISTANCE; MAJOR CLINICAL STUDY; MALE; MASS SCREENING; PRIORITY JOURNAL; AMINO ACID SUBSTITUTION; BLOOD; GENETICS; GLUCOSE BLOOD LEVEL; JAPAN; METABOLISM; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADULT; AMINO ACID SUBSTITUTION; ANTIGENS, CD36; BLOOD GLUCOSE; BLOOD PRESSURE; BODY MASS INDEX; FATTY ACIDS, NONESTERIFIED; FEMALE; HUMAN; INSULIN RESISTANCE; JAPAN; LIPIDS; LIPOPROTEINS; MALE; MIDDLE AGE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 0035172876     PISSN: 00098981     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-8981(01)00658-1     Document Type: Article

References (24)

1. A monoclonal antibody against an erythrocyte ontogenic antigen identifies fetal and adult erythroid progenitors
2. PAS IV, an integral membrane protein of mammary epithelial cells, is related to platelet and endothelial cell CD36 (GP IV)
3. Isolation of the thrombospondin membrane receptor
4. Identification of a platelet membrane glycoprotein as a falciparum malaria sequestration receptor
5. CD36 is a receptor for oxidized low density lipoprotein
6. Cloning of a rat adipocyte membrane protein implicated in binding or transport of long-chain fatty acids that is induced during preadipocyte differentiation. Homology with human CD36
7. Human CD36 is a high affinity receptor for the native lipoproteins HDL, LDL, and VLDL
8. A null mutation in murine CD36 reveals an important role in fatty acid and lipoprotein metabolism
9. Muscle-specific overexpression of FAT/CD36 enhances fatty acid oxidation by contracting muscle, reduces plasma triglycerides and fatty acids, and increases plasma glucose and insulin
10. Identification of the platelet-specific alloantigen, Naka, on platelet membrane glycoprotein IV
11. A platelet membrane glycoprotein (GP) deficiency in healthy blood donors: Naka-platelets lack detectable GPIV (CD36)
12. Expression of GPIV and N(aka) antigen on monocytes in N(aka)-negative subjects whose platelets lack GPIV
13. CD36 as an oxidized LDL receptor
14. Human CD36 deficiency is associated with elevation in low-density lipoprotein-cholesterol
15. A novel polymorphism in glycoprotein IV (replacement of proline-90 by serine) predominates in subjects with platelet GPIV deficiency
16. Molecular basis of CD36 deficiency. Evidence that a 478C → T substitution (proline90 → serine) in CD36 cDNA accounts for CD36 deficiency
17. Homeostasis model assessment: Insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man
18. A prospective analysis of the HOMA model. The Mexico City Diabetes Study
19. Effective amplification of long targets from cloned inserts and human genomic DNA
20. Quantitative trait loci for cellular defects in glucose and fatty acid metabolism in hypertensive rats
21. Genetics of CD36 and the clustering of multiple cardiovascular risk factors in spontaneous hypertension
22. Absence of CD36 mutation in the original spontaneously hypertensive rats with insulin resistance
23. CD36 deficiency associated with insulin resistance
24. Type 1 CD36 deficiency in humans is not associated with insulin resistance syndrome