No complement receptor 1 stumps on podocytes in human glomerulopathies

Kidney International

Volumn 59, Issue 1, 2001, Pages 160-168

  Moll, Solange ^a   Miot, Sylvie ^a   Sadallah, Salima ^a   Gudat, Fred ^a   Mihatsch, Michael J ^a   Schifferli, Jürg A ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

Author keywords

CR1 stump; Focal segmental glomerulosclerosis; Glycoprotein; IgA nephritis; Membranous nephritis; Systemic lupus erythematosus

Indexed keywords

COMPLEMENT; COMPLEMENT COMPONENT C3B RECEPTOR; COMPLEMENT RECEPTOR; EPITOPE;

ARTICLE; CELL MEMBRANE; COMPLEMENT FIXATION; CONTROLLED STUDY; FOCAL GLOMERULOSCLEROSIS; GLOMERULOPATHY; GLOMERULUS; HUMAN; HUMAN TISSUE; IMMUNOGLOBULIN A NEPHROPATHY; IMMUNOHISTOCHEMISTRY; KIDNEY BIOPSY; LUPUS ERYTHEMATOSUS NEPHRITIS; MEMBRANOUS GLOMERULONEPHRITIS; MINIMAL CHANGE GLOMERULONEPHRITIS; PODOCYTE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; PROTEINURIA; RECEPTOR BINDING; STAINING;

EID: 0035172135     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.2001.00476.x     Document Type: Article

References (25)

1. Identification of the membrane glycoprotein that is the C3b receptor of the human erythrocyte, polymorphonuclear leukocyte, B lymphocyte, and monocyte
2. Complement receptor type 1 (C3b/C4b receptor; CD 35) and complement receptor type 2 (C3d/Epstein-Barr virus receptor; CD21)
3. Deficiencies of human complement receptors type 1 (CR1, CD35) and type 2 (CR2, CD21)
4. Immunohistochemical study on the human glomerular C3b receptor in normal kidney and in seventy-five cases of renal diseases
5. Characterization of human C3 receptor as C3b/C4b complement type one (CR1) receptor
6. Identification of membrane-bound CR1 (CD:35) in human urine: Evidence for its release by glomerular podocytes
7. Evaluation of the mechanisms responsible for the reduction in erythrocyte complement receptors when immune complexes form in vivo in primates
8. Erythrocytes transfused into patients with SLE and haemolytic anaemia lose complement receptor type 1 from their cell surface
9. Localization of the complement regulatory proteins in the normal human kidney
10. Complement regulatory proteins in glomerular diseases
11. Complement receptor 1 (CD35) on human reticulocytes: Normal expression in systemic lupus erythematosus and HIV-infected patients
12. Proteolytic cleavage of CR1 on human erythrocytes in vivo: Evidence for enhanced cleavage in AIDS
13. Soluble complement receptor type 1 (CR1) is released from leukocytes by surface cleavage
14. Elastase and metalloproteinase activities regulate soluble complement receptor 1 release
15. Monoclonal antibodies to human complement receptor (CR1) detect defects in glomerular diseases
16. CR1 stump peptide and terminal complement complexes are found in the glomeruli of lupus nephritis patients
17. Mapping epitopes for 20 monoclonal antibodies to CR1
18. Podocalyxin on the glomerular epithelial cells is preserved well in various glomerular diseases
19. Identification of a major sialoprotein in the glycocalyx of human visceral glomerular epithelial cells
20. A monoclonal antibody which blocks the function of factor D of human complement
21. Abnormal podocyte CR1 expression in glomerular diseases: Association with glomerular cell proliferation and monocyte infiltration
22. An anti-peptide antibody that recognizes a neo-antigen in the CR1 stump remaining on erythrocytes after proteolysis
23. Immunohistochemical detection of the terminal C5b-9 complement complex in children with glomerular diseases
24. Immunohistochemical studies of vitronectin, C5b-9, and vitronectin receptor in membranous nephropathy
25. Measurement of C5b-9 in urine in patients with nephrotic syndrome