Regulation of hematopoietic growth factor production by genetically modified human bone marrow stromal cells expressing interleukin-1β antisense RNA

Journal of Interferon and Cytokine Research

Volumn 21, Issue 10, 2001, Pages 851-860

  Hartwig, Udo F ^a   Keller, Ulrich ^b   Huber, Christoph ^a   Peschel, Christian ^b  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY RNA; DNA; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HEMOPOIETIC GROWTH FACTOR; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; LIPOSOME; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; BONE MARROW CELL; CONTROLLED STUDY; CYTOKINE PRODUCTION; DNA TRANSFER; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; GENETIC TRANSFECTION; HEMATOPOIESIS; HUMAN; HUMAN CELL; PRIORITY JOURNAL; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STROMA CELL;

BASE SEQUENCE; BONE MARROW CELLS; CELL LINE; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; INTERLEUKIN-1; INTERLEUKIN-6; INTERLEUKIN-8; LIPOPOLYSACCHARIDES; RNA, ANTISENSE; RNA, MESSENGER; STROMAL CELLS; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0035171908     PISSN: 10799907     EISSN: None     Source Type: Journal    
DOI: 10.1089/107999001753238105     Document Type: Article

References (39)

1. Biologic basis for interleukin-1 in disease
2. Vitro production of IL-1 beta, IL-1 alpha, TNF and IL-2 in healthy subjects: Distribution, effect of cyclooxygenase inhibition and evidence of independent gene regulation
3. Interleukin-1: A gene expression system regulated at multiple levels
4. Proliferation of myeloid progenitor cells in human long-term bone marrow cultures is stimulated by interleukin-1 beta
5. +progenitor cells by stem cell factor, interleukin-1 beta (IL-1 beta), IL-6, IL-3, interferon-gamma, and erythropoietin
6. In vivo modulation with anti-interleukin-1 (IL-1) receptor (p80) antibody 35F5 of the response to IL-1. The relationship of radioprotection, colony-stimulating factor, and IL-6
7. An interleukin-1 receptor antagonist blocks lipopolysaccharide-induced colony-stimulating factor production and early endotoxin tolerance
8. Cytokine regulation of colony-stimulating factor (CSF) production in cultured human synovial fibroblasts. II. Similarities and differences in the control of interleukin-1 induction of granulocyte-macrophage-CSF and granulocyte-CSF production
9. Interleukin-1 regulation of hematopoietic growth factor production by human stromal fibroblasts
10. Interleukin 1 stimulates fibroblasts to synthesize granulocyte-macrophage and granulocyte colony-stimulating factors. Mechanism for the hematopoietic response to inflammation
11. Regulation of cytokine expression by interferon alpha in human bone marrow stromal cells: Inhibition of hematopoietic growth factors and induction of IL-1 receptor antagonist
12. IL-1 alpha and TNF alpha act synergistically to stimulate production of myeloid colony-stimulating factors by cultured human bone marrow stromal cells and cloned stromal cell strains
13. Interleukin-1 alpha upregulates tumor necrosis factor receptors expressed by a human bone marrow stromal cell strain: Implications for cytokine redundancy and synergy
14. Synergy of IL-1 and stem cell factor in radioprotection of mice is associated with IL-1 up-regulation of mRNA and protein expression for c-kit on bone marrow cells
15. Cloning of the human gene for intercellular adhesion molecule 1 and analysis of its 5′-regulatory region. Induction by cytokines and phorbol ester
16. Resistance to fever induction and impaired acute-phase response in interleukin-1 beta deficient mice
17. Conditions controlling the proliferation of haemopoietic stem cells in vitro
18. The essential cells of the hemopoietic microenvironment
19. Long-term human bone marrow cultures
20. A single bone marrow-derived stromal cell type supports the in vitro growth of early lymphoid and myeloid cells
21. A stromal cell line from myeloid long-term bone marrow cultures can support myelopoiesis and lymphopoiesis
22. Systematic analysis of the ability of stromal cell lines derived from different murine adult tissues to support maintenance of hematopoietic stem cells in vitro
23. Simian virus 40-transformed adherent cells from human long-term marrow cultures: Cloned cell lines produce cells with stromal and hematopoietic characteristics
24. Establishment of two permanent human bone marrow stromal cell lines with long-term post irradiation feeder capacity
25. Constitutive and modulated cytokine expression in two permanent human bone marrow stromal cell lines
26. Cloning, sequencing and expression of two distinct human interleukin-1 complementary DNAs
27. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
28. Specific regulation of gene expression by antisense, sense and antigene nucleic acids
29. Regulation of interleukin-6 expression in murine bone marrow stromal cells
30. Regulation of interleukin-8 expression by interleukin-1β, osteotropic hormones, and protein kinase inhibitors in normal human bone marrow stromal cells
31. Structural gene identification and mapping by DNA-mRNA hybrid-arrested cell-free translation
32. A unique mechanism regulating gene expression: Translational inhibition by a complementary RNA transcript (micRNA)
33. Inhibition of thymidine kinase gene expression by anti-sense RNA: A molecular approach to genetic analysis
34. Sandwich ELISA formats designed to detect 17 kDa IL-1 beta significantly underestimate 35 kDa IL-1 beta
35. Generation of biologically active IL-1 beta by proteolytic cleavage of the inactive precursor
36. Secretion of interleukin-1 by acute myeloblastic leukemia cells in vitro induces endothelial cells to secrete colony-stimulating factors
37. Interleukin 1-dependent paracrine granulopoiesis in chronic granulocytic leukemia of the juvenile type
38. Altered levels of interleukin-1 beta and interleukin-1 receptor antagonist in chronic myelogenous leukemia: Clinical and prognostic correlates
39. Alteration in bone marrow adherent layer growth factor expression: A novel mechanism of chronic myelogenous leukemia progression