Mitochondrial transcription factor A and respiratory complex IV increase in response to exercise training in humans

Pflugers Archiv European Journal of Physiology

Volumn 443, Issue 1, 2001, Pages 61-66

  Bengtsson, Jessica ^a,b   Gustafsson, Thomas ^a,b   Widegren, Ulrika ^a,b   Jansson, Eva ^b   Sundberg, Carl Johan ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Ischemia; Mitochondrial biogenesis; Mitochondrial transcription factor A (Tfam); Protein expression; Skeletal muscle; Tfam

Indexed keywords

CITRATE SYNTHASE; CYTOCHROME C OXIDASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR A; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BIOGENESIS; CONTROLLED STUDY; CYCLING; ENZYME ACTIVITY; EXERCISE; HUMAN; HUMAN TISSUE; MALE; MITOCHONDRION; MUSCLE BIOPSY; MUSCLE BLOOD FLOW; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RESPIRATORY CHAIN; TRAINING; VASTUS LATERALIS MUSCLE;

ADULT; CITRATE (SI)-SYNTHASE; DNA-BINDING PROTEINS; ELECTRON TRANSPORT COMPLEX I; ELECTRON TRANSPORT COMPLEX IV; ENERGY METABOLISM; EXERCISE; HUMANS; MALE; MITOCHONDRIA, MUSCLE; MITOCHONDRIAL PROTEINS; NADH, NADPH OXIDOREDUCTASES; NUCLEAR PROTEINS; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; XENOPUS PROTEINS;

EID: 0035170361     PISSN: 00316768     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004240100628     Document Type: Article

References (30)

1. Muscle electrolytes in man
2. Molecular and cellular adaptation of muscle in response to exercise: Perspectives of various models
3. Restoration of fast muscle characteristics following cessation of chronic stimulation: Physiological, histochemical and metabolic changes during slow-to-fast transformation
4. Priming of human mitochondrial DNA replication occurs at the light-strand promoter
5. Calf muscle adaptation to peripheral vascular disease
6. Addition of a 29 residue carboxyl-terminal tail converts a simple HMG box-containing protein into a transcriptional activator
7. Dynamic exercise in man as influenced by experimental restriction of blood flow in the working muscles
8. A transcription factor required for promoter recognition by human mitochondrial RNA polymerase. Accurate initiation at the heavy- and light-strand promoters dissected and reconstituted in vitro
9. Effects of contractile activity on mitochondrial transcription factor A expression in skeletal muscle
10. Enzyme activities, fibre types and capillarization in calf muscles of patients with intermittent claudication
11. Chronic stimulation of rat skeletal muscle induces coordinate increases in mitochondrial and nuclear mRNAs of cytochrome-c-oxidase subunits
12. Calf muscle adaptation in intermittent claudication. Side-differences in muscle metabolic characteristics in patients with unilateral arterial disease
13. Low levels of mitochondrial transcription factor A in mitochondrial DNA depletion
14. Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice
15. Coenzyme Q10 content in different parts of the normal human heart
16. Induction of nuclear respiratory factor-1 expression by an acute bout of exercise in rat muscle
17. Similarity of human mitochondrial transcription factor 1 to high mobility group proteins
18. Related mRNAs of enzymes involved in energy metabolism and mtDNA are increased in endurance-trained athletes
19. Skeletal muscle adaptability: Significance for metabolism and performance
20. Mitochondrial DNA maintenance in vertebrates
21. Kinetic parameters of cytochrome c oxidase in rat skeletal muscle: Effect of endurance training
22. Exercise and training during graded leg ischaemia in healthy man
23. Is hypoxia a stimulus for synthesis of oxidative enzymes and myoglobin?
24. NRF-1, an activator involved in nuclear-mitochondrial interactions, utilizes a new DNA-binding domain conserved in a family of developmental regulators
25. Activation of the human mitochondrial transcription factor A gene by nuclear respiratory factors: A potential regulatory link between nuclear and mitochondrial gene expression in organelle biogenesis
26. Divergent effects of exercise on metabolic and mitogenic signaling pathways in human skeletal muscle
27. Adaptation of mitochondrial gene expression to changing cellular energy demands
28. Stimulation of mitochondrial gene expression and proliferation of mitochondria following impairment of cellular energy transfer by inhibition of the phosphocreatine circuit in rat hearts
29. Effects of inhibition of mitochondrial protein synthesis in skeletal muscle