Molecular immunologic strategies to identify antigens and B-cell responses unique to multiple sclerosis

Archives of Neurology

Volumn 58, Issue 1, 2001, Pages 43-48

  Gilden, D H ^a   Burgoon, M P ^a   Kleinschmidt DeMasters, B K ^a   Williamson, R A ^a   Ghausi, O ^a   Burton, D R ^a   Owens, G P ^a  

^a UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; ANTIGEN; CALGRANULIN; COMPLEMENTARY DNA; CRYSTALLIN; DNA; EPITOPE; IMMUNOGLOBULIN ANTIBODY; IMMUNOGLOBULIN G; MESSENGER RNA; MYELIN; PEPTIDE; PROTEIN;

B LYMPHOCYTE; B LYMPHOCYTE ACTIVATION; CEREBROSPINAL FLUID; COMPLEMENTARITY DETERMINING REGION; DNA LIBRARY; HUMAN; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; MULTIPLE SCLEROSIS; PHAGE DISPLAY; PRIORITY JOURNAL; REVIEW;

EID: 0035170173     PISSN: 00039942     EISSN: None     Source Type: Journal    
DOI: 10.1001/archneur.58.1.43     Document Type: Review

References (19)

1. Immunopathology of multiple sclerosis: Report on an international meeting held at the Institute of Neurology of the University of Vienna
2. Multiple sclerosis: Lessons from neuropathology
3. H4 germline segments in an acute multiple sclerosis brain
4. Comparison of immunoglobulin G heavy-chain sequences in MS and SSPE brains reveals an antigen-driven response
5. Cloning the antibody response in humans with inflammatory CNS disease: Analysis of the expressed IgG repertoire in subacute sclerosing panencephalitis brain reveals diseaserelevant antibodies that recognize specific measles virus antigens
6. B cell repertoire diversity and clonal expansion in multiple sclerosis brain lesions
7. H genes of B cells from cerebrospinal fluid in multiple sclerosis
8. Accumulation of clonally related B lymphochtes in the cerebrospinal fluid of multiple sclerosis patients
9. Strategies to identify sequences or antigens unique to multiple sclerosis
10. Isolation and characterization of an oligodendrocyte precursor-derived B-cell epitope in multiple sclerosis
11. Human antibodies from combinatorial libraries
12. Human monoclonal antibodies against a plethora of viral pathogens from single combinatorial libraries
13. Humap anti-nicotinic acetylcholine receptor recombinant Fab fragments isolated from thymus-derived phage display libraries from myasthenia gravis patients reflect predominant specificities in serum and block the action of pathlogenic serum antibodies
14. Cloning the antibody response in humans with inflammatory CNS disease: Isolation of measles virus-specific antibodies from phage display libraries of a subacute sclerosing panencephalitis brain
15. Cloning the antibody re sponse in humans with chromic inflammatory disease: Immunopanning of subacute sclerosing panencephalitis (SSPE) brain sections with antibody phage libraries prepared from SSPE brain enriches for antibody recognizing measles antigen in situ
16. Sub-acute sclerosing panencephalitis
17. Searching fort peptide ligands with an epitope library
18. Molecular approach to find target(s) for oligoclonal bands in multiple sclerosis
19. The search for unrecognized pathogens