Pharmacokinetics of cefcapene pivoxil and AS-924 in gastrectomized patients

International Journal of Antimicrobial Agents

Volumn 18, Issue 5, 2001, Pages 489-494

  Fujimoto, Mikio ^a  

^a Fujiidera City Hospital   (Japan)

Author keywords

AS 924; Cefcapene pivoxil; Gastrectomy; Pharmacokinetics

Indexed keywords

ANTIBIOTIC AGENT; CEFCAPENE; CEFCAPENE PIVOXIL; CEFTIZOXIME; CEFTIZOXIME ALAPIVOXIL; CEFTIZOXIME ARAPIVOXIL; CEPHEM DERIVATIVE; PRODRUG; UNCLASSIFIED DRUG;

ADULT; AGED; AREA UNDER THE CURVE; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG SOLUBILITY; GASTRECTOMY; HUMAN; PRIORITY JOURNAL; STOMACH JUICE; STOMACH PH; SURGICAL TECHNIQUE; TOTAL STOMACH RESECTION;

AGED; CEFTIZOXIME; CEPHALOSPORINS; GASTRECTOMY; HUMANS; MIDDLE AGED; PRODRUGS; STOMACH NEOPLASMS;

EID: 0035169526     PISSN: 09248579     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0924-8579(01)00446-0     Document Type: Article

References (6)

1. In vitro antibacterial activity of S-1106, active form of the new oral cephem antibiotic S-1108
2. AS-924, a novel orally active bifunctional prodrug of ceftizoxime; Synthesis and relationship between physicochemical properties and oral absorption
3. Phase I study of S-1108, a new ester-type oral cephem antibiotic
4. Effects of food intake and age on the pharmacokinetics of AS-924, a novel ester-type cephem antibiotic. Comparison with cefpodoxime proxetil
5. Pharmacokinetic studies of a new oral cephem T-2588. Pharmacokinetics in gastrectomized volunteers and renal excretion system in healthy volunteers
6. Determination of S-1006 and related compounds in human plasma and urine by high-performance liquid chromatography