Single-copy IMH3 allele is sufficient to confer resistance to mycophenolic acid in Candida albicans and to mediate transformation of clinical Candida species

Infection and Immunity

Volumn 69, Issue 1, 2001, Pages 108-114

  Beckerman, J ^a   Chibana, H ^a   Turner, J ^a   Magee, P T ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MYCOPHENOLIC ACID;

ANTIBIOTIC RESISTANCE; ANTIFUNGAL ACTIVITY; ARTICLE; CANDIDA ALBICANS; CANDIDIASIS; FUNGAL GENETICS; GENE SEQUENCE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL;

ALLELES; ANTI-BACTERIAL AGENTS; BASE SEQUENCE; CANDIDA ALBICANS; CHROMOSOME MAPPING; DRUG RESISTANCE, MICROBIAL; EXONS; IMP DEHYDROGENASE; MOLECULAR SEQUENCE DATA; MUTATION; MYCOPHENOLIC ACID;

EID: 0035167091     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.69.1.108-114.2001     Document Type: Article

References (30)

1. A method for gene disruption that allows repeated use of URA3 selection in the construction of multiply disrupted yeast strains
2. Basic local alignment search tool
3. Isolation and nucleotide sequence of an autonomously replicating sequence (ARS) element functional in Candida albicans and Saccharomyces cerevisiae
4. Putative virulence factors of Candida albicans
5. Isogenic strain construction and gene mapping in Candida albicans
6. Linkage of adhesion, filamentous growth, and virulence in Candida albicans to a single gene, INT1
7. Genomic profiling of drug sensitivities via induced haploinsufficiency
8. Multiple LTR-retrotransposon families in the asexual yeast Candida albicans
9. Genetic analysis of prototrophic natural variants of Candida albicans
10. The ARG4 gene of Candida albicans
11. Evidence for mating of the "asexual" yeast Candida albicans in a mammalian host
12. Genetic analysis of Candida albicans: Identification of different isoleucine-valine, methionine, and arginine alleles by complementation
13. Pathogenicity of Candida albicans auxotrophic mutants in experimental infections
14. Overexpression of a cloned IMP dehydrogenase gene of Candida albicans confers resistance to the specific inhibitor mycophenolic acid
15. Silencers, silencing, and heritable transcriptional states
16. Altered expression of selectable marker URA3 in gene-disrupted Candida albicans strains complicates interpretation of virulence studies
17. Induction of mating in Candida albicans by construction of MTLa and MTLα strains
18. The use of molecular techniques for epidemiologic typing of Candida species
19. Parasexual genetic analysis of Candida albicans by spheroplast fusion
20. Mechanisms of resistance to azole antifungal agents in Candida albicans isolates from AIDS patients involve specific multidrug transporters
21. The CUG codon is decoded in vivo as serine and not leucine in Candida albicans
22. Hybridization of Candida albicans through fusion of protoplasts
23. Molecular cloning and analysis of autonomous replicating sequence of Candida maltosa
24. Genetics of Candida albicans
25. High-frequency switching of colony morphology in Candida albicans
26. Host-induced, stage-specific virulence gene activation in Candida albicans during infection
27. A molecular genetic system for the pathogenic yeast Candida dubliniensis
28. Candida dubliniensis sp. nov.: Phenotypic and molecular characterization of a novel species associated with oral candidosis in HIV-infected individuals
29. Rapid differentiation of closely related Candida species and strains by pyrolysis-mass spectrometry and Fourier transform-infrared spectroscopy
30. Increased mRNA levels of ERG16, CDR, and MDR1 correlate with increases in azole resistance in Candida albicans isolates from a patient infected with human immunodeficiency virus