Presence of natural killer-cell clones with variable proliferative capacity in chronic active Epstein-Barr virus infection

Pathology International

Volumn 51, Issue 10, 2001, Pages 778-785

  Nagata, Hiroshi ^a   Numata, Tsutomu ^a   Konno, Akiyoshi ^a   Mikata, Ittaku ^b   Kurasawa, Kazuhiro ^a   Hara, Satoru ^a   Nishimura, Miki ^a   Yamamoto, Kohtaro ^c   Shimizu, Norio ^c  

^a CHIBA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NARITA RED CROSS HOSPITAL   (Japan)

^c TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

Cell line; Epstein Barr virus; Lymphoma; Natural killer cell; Transformation

Indexed keywords

ANTINEOPLASTIC AGENT; CYCLOSPORIN; PREDNISONE; RECOMBINANT INTERLEUKIN 2;

ADULT; ARTICLE; CASE REPORT; CELL CLONE; CELL LINEAGE; CELL PROLIFERATION; CERVICAL LYMPH NODE; DISEASE ASSOCIATION; DISEASE COURSE; DRUG EFFECT; DRUG MEGADOSE; EPSTEIN BARR VIRUS; FEMALE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOPHENOTYPING; INTERSTITIAL PNEUMONIA; LONG TERMINAL REPEAT; LYMPHOID CELL; NATURAL KILLER CELL; PRIORITY JOURNAL; SEPSIS; SOUTHERN BLOTTING; T CELL LYMPHOMA; TREATMENT OUTCOME; TUMOR BIOPSY; ULCER; VIRUS INFECTION;

ADULT; BLOTTING, SOUTHERN; CELL LINE; CELL TRANSFORMATION, NEOPLASTIC; CHRONIC DISEASE; CLONE CELLS; EPSTEIN-BARR VIRUS INFECTIONS; FEMALE; GENE REARRANGEMENT; HUMANS; IN SITU HYBRIDIZATION; KILLER CELLS, NATURAL; LYMPH NODES; LYMPHOMA, T-CELL; NASOPHARYNX; NOSE NEOPLASMS; RNA, VIRAL;

EID: 0035166556     PISSN: 13205463     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1827.2001.01276.x     Document Type: Article

References (36)

1. Evidence for active Epstein-Barr virus infection in patients with persistent, unexplained illness: Elevated anti-early antigen antibodies
2. Chronic Epstein-Barr virus infection associated with fever and interstitial pneumonitis. Clinical and serological features and responses to antiviral chemotherapy
3. The chronic mononucleosis syndrome
4. Severe chronic active Epstein-Barr virus infection syndrome
5. Chronic active Epstein-Barr virus infection in children in Japan
6. T-cell lymphomas containing Epstein-Barr viral DNA in patients with chronic Epstein-Barr virus infections
7. Clinicopathologic study of severe chronic active Epstein-Barr virus infection that developed in association with lymphoproliferative disorder and/or hemophagocytic syndrome
8. A syndrome of peripheral blood T-cell infection with Epstein-Barr virus (EBV) followed by EBV-positive T-cell lymphoma
9. +T-cell lymphoproliferative disorder following acute/chronic EBV infection: A distinct clinicopathologic syndrome
10. Epstein-Barr virus genome-positive T lymphocytes in a boy with chronic active EBV infection associated with Kawasaki-like disease
11. CD-3 negative lymphoproliferative disease of granular lymphocytes containing Epstein-Barr viral DNA
12. Clonal T-cell lymphoproliferation containing Epstein-Barr (EB) virus DNA in a patient with chronic active EB virus infection
13. CD-3 negative lymphoproliferative disease of granular lymphocytes in a girl with an unusual pattern of anti-Epstein-Barr virus antibodies
14. Epstein-Barr virus (EBV)-carrying and -expressing T-cell lines established from severe chronic active EBV infection
15. Clonal lymphoproliferation following chronic active Epstein-Barr virus infection and hypersensitivity to mosquito bites
16. Restricted diversification of T-cells in chronic active Epstein-Barr virus infection: Potential inclination to T-lymphoproliferative disease
17. Characterization of Epstein-Barr virus (EBV)-infected natural killer (NK) cell proliferation in patients with severe mosquito allergy; establishment of an IL-2-dependent NK-like cell line
18. Blood stem-cell transplantation for chronic active Epstein-Barr virus with lymphoproliferation
19. Morphology, immunophenotype, and distribution of latently and/or productively Epstein-Barr virus-infected cells in acute infectious mononucleosis: Implications for the interindividual infection route of Epstein-Barr virus
20. Strict lymphotropism of Epstein-Barr virus during acute infectious mononucleosis in nonimmunocompromised individuals
21. Characterization of novel natural killer (NK)-cell and γδ T-cell lines established from primary lesions of nasal T/NK-cell lymphomas associated with the Epstein-Barr virus
22. Chronic, symptomatic Epstein-Barr virus infection
23. Description of an in situ hybridization methodology for detection of Epstein-Barr virus RNA in paraffin-embedded tissues, with a survey of normal and neoplastic tissues
24. Complexity of human T-cell antigen receptor β-chain constant- and variable-region gene
25. Human T-cell γ chain genes. Organization, diversity, and rearrangement
26. Rearrangement of T-cell δ locus in lymphoproliferative disorders
27. Immunoglobulin gene rearrangement and cell surface antigen expression in acute lymphocytic leukemias of T cell and B cell precursor origins
28. The structure of the termini of the Epstein-Barr virus as a marker of clonal cellular proliferation
29. Expression of cytoplasmic CD3ε proteins in activated human adult natural killer (NK) cells and CD3γ, δ, ε complexes in fetal NK cells
30. Nasal T/natural killer (NK)-cell lymphomas are derived from Epstein-Barr virus-infected cytotoxic lymphocytes of both NK- and T-cell lineage
31. Defective activity of Epstein-Barr virus (EBV) specific cytotoxic T lymphocytes in children with chronic active EBV infection and in their parents
32. Summary: Symposium on Epstein-Barr virus induced lymphoproliferative diseases in immunodeficient patients
33. Epstein-Barr virus (EBV) induced polyclonal and monoclonal B-cell lymphoproliferative disease occurring after renal transplantation
34. Epstein-Barr virus- associated B-cell proliferation of diverse clonal origins after bone marrow transplantation in a 12-year-old patient with severe combined immunodeficiency
35. Clonal analysis of transplant-associated lymphoproliferations based on the structure of the genomic termini of the Epstein-Barr virus
36. Correlative morphologic and molecular genetic analysis demonstrates three categories of post-transplantation lymphoproliferative disorders