Potent expansion of human natural killer T cells using α-galactosylceramide (KRN7000)-loaded monocyte-derived dendritic cells, cultured in the presence of IL-7 and IL-15

Journal of Immunological Methods

Volumn 247, Issue 1-2, 2001, Pages 61-72

  Van Der Vliet, Hans J J ^a   Nishi, Nobusuke ^a   Koezuka, Yasuhiko ^b   Von Blomberg, B Mary E ^a   Van Den Eertwegh, Alfons J M ^a   Porcelli, Steven A ^c   Pinedo, Herbert M ^a   Scheper, Rik J ^a   Giaccone, Giuseppe ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b KIRIN BREWERY CO LTD   (Japan)

^c ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

galactosylceramide; CD1d; Dendritic cells; IL 15; IL 7; NKT cells

Indexed keywords

CD1 ANTIGEN; CYTOKINE; FAS ANTIGEN; GALACTOSYLCERAMIDE; GRANZYME B; INTERLEUKIN 15; INTERLEUKIN 4; INTERLEUKIN 7; LIGAND; T LYMPHOCYTE RECEPTOR;

ADULT; ALPHA CHAIN; ANTIGEN EXPRESSION; ANTIGEN PRESENTING CELL; ARTICLE; BETA CHAIN; CULTURE MEDIUM; CYTOTOXICITY; DENDRITIC CELL; FEMALE; HUMAN; IMMUNE RESPONSE; MALE; MONOCYTE; MONONUCLEAR CELL; NATURAL KILLER CELL; NORMAL HUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; TECHNIQUE;

ADULT; ANTIGENS, CD1; B-LYMPHOCYTES; CELLS, CULTURED; DENDRITIC CELLS; FEMALE; GALACTOSYLCERAMIDES; HUMANS; INTERLEUKIN-15; INTERLEUKIN-7; KILLER CELLS, NATURAL; LEUKOCYTES, MONONUCLEAR; MALE; MONOCYTES; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA;

EID: 0035166455     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-1759(00)00272-6     Document Type: Article

References (37)

1. IL-15 has stimulatory activity for the induction of B cell proliferation and differentiation
2. + T cells in the absence of TCR-ligation
3. MHC class I-like, class II-like and CD1 molecules: Distinct roles in immunity
4. Expression of a nonpolymorphic MHC class I-like molecule, CD1d, by human intestinal epithelial cells
5. Distinct roles for signals relayed through the common cytokine receptor γ chain and interleukin 7 receptor α chain in natural T cell development
6. CD1d-mediated recognition of an α-galactosylceramide by natural killer T cells is highly conserved through mammalian evolution
7. Interleukin-15 protects from lethal apoptosis in vivo
8. Two classes of CD1 genes
9. Peptide binding and presentation by mouse CD1
10. + T cells produce large amounts of IL-4 and IFN-γ upon activation by anti-CD3 or CD1
11. Diverse CD1d-restricted reactivity patterns of human T cells bearing 'invariant' AV24BV11 TCR
12. Requirement for Vα14 NKT cells in IL-12-mediated rejection of tumors
13. - subset
14. - T cells
15. - T cells
16. Dendritic cells: Unique leukocyte populations which control the primary immune response
17. Evolutionary origin and diversification of the mammalian CD1 antigen genes
18. Interleukin-15 preferentially promotes the growth of intestinal intraepithelial lymphocytes bearing gamma delta T cell receptor in mice
19. Natural killer-like nonspecific tumor cell lysis mediated by specific ligand-activated Vα14 NKT cells
20. Diverse immunological and hematological effects of interleukin 7: Implications for clinical application
21. - T cells in mice and humans
22. Interleukin-7 inhibits apoptosis of mouse malignant T-lymphoma cells by both suppressing the CPP32-like protease activation and inducing the Bcl-2 expression
23. IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation
24. -/- mice
25. + NK T cells associated with disease development in autoimmune-prone mice
26. Activation of human Vα24NKT cells by α-glycosylceramide in a CD1d-restricted and Vα24TCR-mediated manner
27. +-T cells in vitro
28. + cell development
29. - α/β T cells demonstrates preferential use of several Vβ genes and an invariant α chain
30. The CD1 family: A third lineage of antigen presenting molecules
31. How do cytotoxic lymphocytes kill their targets?
32. CD1d-restricted recognition of synthetic glycolipid antigens by human natural killer T cells
33. Selective reduction of T cells bearing invariant Vα24JαQ antigen receptor in patients with systemic sclerosis
34. +-T cells
35. Human natural killer T cells acquire a memory-activated phenotype before birth
36. Cytokine-induced survival of activated T cells in vitro and in vivo
37. Extreme Th1 bias of invariant Vα24JαQ T cells in type I diabetes