Genomic and allelic expression status of the p73 gene in human neuroblastoma

Medical and Pediatric Oncology

Volumn 36, Issue 1, 2001, Pages 45-47

  Norris, M D ^a   Gilbert, J ^b   Smith, S A ^a   Marshall, G M ^b   Salwen, H ^a   Cohn, Susan L ^b   Haber, M ^a,c  

^a SYDNEY CHILDREN'S HOSPITAL   (Australia)

^b NORTHWESTERN UNIVERSITY   (United States)

^c CHILDREN S CANCER INSTITUTE AUSTRALIA FOR MEDICAL RESEARCH   (Australia)

Author keywords

Neuroblastoma; p73 gene

Indexed keywords

PROTEIN P53; PROTEIN P73;

ALLELISM; CONFERENCE PAPER; CONTROLLED STUDY; GENE DELETION; GENE EXPRESSION; GENE MUTATION; GENETIC ASSOCIATION; GENETIC TRANSCRIPTION; GENOME; HETEROZYGOSITY LOSS; HUMAN; HUMAN CELL; NEUROBLASTOMA; PRIORITY JOURNAL; SEQUENCE HOMOLOGY;

ALLELES; CHROMOSOMES, HUMAN, PAIR 1; DNA, COMPLEMENTARY; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, TUMOR SUPPRESSOR; HUMANS; LOSS OF HETEROZYGOSITY; LYMPHOCYTES; NEOPLASM PROTEINS; NEUROBLASTOMA; NUCLEAR PROTEINS; PROTEIN ISOFORMS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, NEOPLASM; TUMOR STEM CELLS; TUMOR SUPPRESSOR PROTEINS;

EID: 0035166423     PISSN: 00981532     EISSN: None     Source Type: Journal    
DOI: 10.1002/1096-911X(20010101)36:1<45::AID-MPO1012>3.0.CO;2-E     Document Type: Conference Paper

References (10)

1. Wild-type p53 protein undergoes cytoplasmic sequestration in undifferentiated neuroblastomas but not in differentiated tumors
2. Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers
3. p73 is a human p53-related protein that can induce apoptosis
4. Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
5. Constitutional 1p36 deletion in a child with neuroblastoma
6. Evidence for two tumour suppressor loci on chromosomal bands 1p35-369 involved in neuroblastoma: One probably imprinted, another associated with N-myc amplification
7. Search for mutations and examination of allelic expression imbalance of the p73 gene at 1p36.33 in human lung cancers
8. Mutation, allelotyping and transcription analyses of the p73 gene in prostatic carcinoma
9. A mutiplex PCR assay for routine evaluation of deletion of the short arm of chromosome 1 in neuroblastoma