Rac1 regulates heat shock responses by reorganization of vimentin filaments: Identification using MALDI-TOF MS

Cell Death and Differentiation

Volumn 8, Issue 11, 2001, Pages 1093-1102

  Lee, S Y ^a   Song, E J ^a   Kim, H J ^a   Kang, H J ^a   Kim, J H ^b   Lee, K J ^a  

^a Ewha Womans University   (South Korea)

^b Gwangju Institute of Science and Technology (GIST)   (South Korea)

Author keywords

Heat shock; MALDI TOF MS; Rac1; SAPK JNK activation; Thermotolerance; Vimentin

Indexed keywords

ACTIN; HEAT SHOCK PROTEIN; MUTANT PROTEIN; RAC1 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; TRYPSIN; VIMENTIN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CELL LINE; COMPARATIVE STUDY; CONTROLLED STUDY; ENZYME ACTIVATION; FIBROBLAST; HEAT SHOCK; HEAT SHOCK RESPONSE; HEAT TOLERANCE; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; RAT; SIGNAL TRANSDUCTION; TWO DIMENSIONAL GEL ELECTROPHORESIS;

ANIMALS; CELL LINE; FIBROBLASTS; HEAT-SHOCK RESPONSE; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; MUTATION; RAC1 GTP-BINDING PROTEIN; RATS; SIGNAL TRANSDUCTION; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; VIMENTIN;

EID: 0035166170     PISSN: 13509047     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cdd.4400923     Document Type: Article

References (33)

1. The function of heat-shock proteins in stress tolerance: Degradation and reactivation of damaged proteins
2. Thermotolerance inhibits various stress-induced apoptosis in NIH3T3 cells
3. The chaperone function of hsp70 is required for protection against stress-induced apoptosis
4. Clinical implications of the stress response
5. Small GTP-binding proteins and the regulation of the actin cytoskeleton
6. Activation of the NADPH oxidase involves the small GTP-binding protein p21rac1
7. The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF
8. The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway
9. Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs
10. Rac1 regulates a cytokine-stimulated, redox-dependent pathway necessary for NF-κB activation
11. The MAPK signaling cascade
12. Protein kinase cascades activated by stress and inflammatory cytokines
13. Rho-like GTPases in tumor cell invasion
14. An essential role for Rho, Rac, and Cdc42 GTPases in cell cycle progression through G1
15. Rac GTPase activity is essential for EGF-induced mitogenesis
16. Fas- or ceramide-induced apoptosis is mediated by a Rac1-regulated activation of Jun N-terminal kinase/p38 kinases and GADD153
17. Tiam1 is involved in the regulation of bufalin-induced apoptosis in human leukemia cells
18. Heat shock stress induces cleavage and activation of PAK2 in apoptotic cells
19. Rac1 regulates stress-induced, redox-dependent heat shock factor activation
20. The stress-activated protein kinase pathway mediates cell death following injury induced by cis-platinum, UV irradiation or heat
21. Hsp70 prevents activation of stress kinases
22. Role of the human heat shock protein hsp70 in protection against stress-induced apoptosis
23. Heat shock and ceramide have different apoptotic pathways
24. Balance between activities of Rho kinase and type 1 protein phosphatase modulates turnover of phosphorylation and dynamics of desmin/vimentin filaments
25. PDGF induces reorganization of vimentin filaments
26. Characterization of the nucleic acid binding region of the intermediate filament protein vimentin by fluorescence polarization
27. Identification of the amino acid residues of the amino terminus of vimentin responsible for DNA binding by enzymatic and chemical sequencing and analysis by MALDI-TOF
28. 2 production requires the activation of phosphatidylinositol 3-kinase
29. Heat shock activates c-Src tyrosine kinases and phosphatidylinositol 3-kinase in NIH3T3 fibroblasts
30. Suppression of Ras transformation by serum response factor
31. Cytoskeletal association of the A and B nucleoside diphosphate kinases of interphasic but not mitotic human carcinoma cell lines: Specific nuclear localization of the B subunit
32. Modification of cysteine residues by alkylation. A tool in peptide mapping and protein identification
33. Oxidative modification of nucleoside diphosphate kinase and its identification by MALDI-TOF MS