Sarcomatoid renal cell carcinoma: Basic biology, clinical behavior and response to therapy

Urologic Oncology

Volumn 6, Issue 6, 2001, Pages 231-238

  Chao, Debby ^a   Zisman, Amnon ^a   Freedland, Stephen J ^a   Pantuck, Allan J ^a   Said, Jonathan W ^a   Belldegrun, Arie S ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b School of Medicine ^*  (United States)

Author keywords

Genetic aberrations; Prognostic factors; Sarcomatoid renal cell carcinoma; Treatment, IL 2

Indexed keywords

ALPHA INTERFERON; ANDROGEN; ANTINEOPLASTIC AGENT; CISPLATIN; CYCLOPHOSPHAMIDE; DACARBAZINE; DOXORUBICIN; ELLIPTINIUM; HYDROXYUREA; IFOSFAMIDE; LOMUSTINE; MEDROXYPROGESTERONE; RECOMBINANT INTERLEUKIN 2; STREPTOZOCIN; VINCRISTINE; VINDESINE;

ANGIOGRAPHY; CANCER DIAGNOSIS; CANCER SURVIVAL; CARCINOSARCOMA; CHROMOSOME ABERRATION; CLINICAL FEATURE; COMPUTER ASSISTED TOMOGRAPHY; DIFFERENTIAL DIAGNOSIS; DRUG MEGADOSE; ELECTRON MICROSCOPY; EPITHELIUM CELL; GENETIC DISORDER; HISTOLOGY; HUMAN; IMMUNOHISTOCHEMISTRY; KIDNEY CARCINOMA; KIDNEY EPITHELIUM; KIDNEY SARCOMA; MALIGNANT TRANSFORMATION; PRIORITY JOURNAL; PROGNOSIS; REVIEW; SARCOMATOID RENAL CELL CARCINOMA; TREATMENT OUTCOME; TUMOR ASSOCIATED LEUKOCYTE;

EID: 0035165834     PISSN: 10781439     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1078-1439(01)00125-9     Document Type: Review

References (59)

1. Diagnosis and management of renal cell carcinoma: A clinical and pathologic study of 309 cases
2. Sarcomatoid renal carcinoma
3. Sarcomatoid renal cell carcinoma. A treatable entity
4. Sarcomatoid renal cell carcinoma: The chromophobe connection
5. Carcinosarcoma
6. Carcinosarcoma of the renal pelvis
7. Sarcoma of the kidney
8. Renal carcino-sarcoma, true and false
9. Sarcomas and sarcomatoid and mixed malignant tumors of the kidney in adults. 3
10. Sarcomatoid renal carcinoma: The final common dedifferentiation pathway of renal epithelial malignancies
11. Sarcomatoid renal cell carcinoma: Clinicopathologic. A study of 42 cases
12. Sarcomatoid renal cell carcinoma: Biologic behavior, prognosis, and response to combined surgical resection and immunotherapy
13. Sarcomatoid carcinoma of the kidney
14. An unusual oncocytic renal cell tumor with sarcomatoid foci and osteogenic differentiation
15. Fine-needle aspiration cytology of sarcomatoid renal cell carcinoma: A morphologic and immunocytochemical study of 15 cases
16. Sarcomatoid collecting duct carcinoma: A clinicopathologic and immunohistochemical study of 5 cases
17. A case of chromophobe renal cell carcinoma with sarcomatoid foci and a small daughter lesion
18. Sarcomatous transformation of chromophobe cell renal carcinoma
19. Chromophobe cell renal carcinomas with sarcomatoid areas
20. Sarcomatoid renal cell carcinoma: A study of its proliferative activity
21. Sarcomatoid renal cell carcinoma: An immunohistochemical study of 18 cases
22. Osteogenic and sarcomatoid differentiation of a renal cell carcinoma
23. Sarcomatoid renal carcinoma with angiosarcomatoid component
24. Sarcomatoid renal tumors: Clinicopathologic correlation of three cases
25. Ultrastructural study of a sarcomatoid variant of renal cell carcinoma
26. Immunohistochemistry and lectin histochemistry in sarcomatoid renal cell carcinoma: A comparison with classical renal cell carcinoma
27. Immunomorphological characteristics of renal cell carcinoma
28. Renal sarcoma and sarcomatoid renal cell carcinoma: CT and angiographic features
29. Comparative genomic hybridization reveals frequent chromosome 13q and 4q losses in renal carcinomas with sarcomatoid transformation
30. Prognostic implications of cytogenetic findings in kidney cancer
31. Loss of alleles of loci on the short arm of chromosome 3 in renal cell carcinoma
32. Molecular analysis of genetic changes in the origin and development of renal cell carcinoma
33. Allelotype of renal cell carcinoma
34. Histopathological, cytogenetic, and molecular characterization of renal cortical tumors
35. Genetic aberrations detected by comparative genomic hybridization are associated with clinical outcome in renal cell carcinoma
36. The genetic locus NRC-1 within chromosome 3p12 mediates tumor suppression in renal cell carcinoma independently of histological type, tumor microenvironment, and VHL mutation
37. Identification of intragenic mutations in the von Hippel-Lindau disease tumour suppressor gene and correlation with disease phenotype
38. Mutations of the p53 gene and p53 protein overexpression are associated with sarcomatoid transformation in renal cell carcinomas
39. Chromosome aberrations in renal tumors detected by fluorescence in situ hybridization
40. Immunohistochemical expression of p53 and bcl-2 proteins is not associated with sarcomatoid change in renal cell carcinoma
41. Loss of heterozygosity occurs centromeric to RB without associated abnormalities in the retinoblastoma gene in tumors from patients with metastatic renal cell carcinoma
42. Expression of the retinoblastoma gene product in renal tumors
43. Comparison of chromosomal aberrations detected by fluorescence in situ hybridization with clinical parameters, DNA ploidy and Ki67 expression in renal cell carcinoma
44. Prognostic value of Ki-67 expression in renal cell carcinoma
45. Value of immunohistochemical Ki-67 and p53 determinations as predictive factors of outcome in renal cell carcinoma
46. Prognostic indicators for renal cell carcinoma: A multivariate analysis of 643 patients using the revised 1997 TNM staging criteria
47. Sarcomatoid renal cell carcinoma metastatic to the heart: Report of a case
48. Solitary left ventricle metastasis by renal cell carcinoma with sarcomatoid features
49. Metastatic renal cell carcinoma invading right ventricular myocardium without caval involvement
50. Prognostic factors for survival in patients with metastatic renal cancer treated with biological response modifiers
51. Renal cell carcinoma II. Histological indicators of prognosis
52. Impact of histology on the treatment outcome of metastatic or recurrent renal cell carcinoma
53. Long-term survival after surgery for recurrent advanced sarcomatoid renal carcinoma
54. Sarcomatoid renal cell carcinoma: A case of spontaneous regression of metastasis
55. Treatment of sarcomatoid renal cell carcinoma: Is there a role for chemotherapy?
56. Phase II trial of combination chemotherapy with decarbazine, cyclophosphamide, cisplatin, doxorubicin, and vindesine (DECAV) in advanced renal cell cancer
57. Expanding the indications for surgery and adjuvant IL-2-based immunotherapy in patients with renal cell carcinoma
58. Assessing genetic heterogeneity of renal cell tumors
59. Molecular differential diagnosis of renal carcinoma from microscopes to micro satellites