Concentration-dependent phorbol stimulation of PKCα localization at the nucleus or subplasmalemma in A7r5 cells

Pflugers Archiv European Journal of Physiology

Volumn 443, Issue 1, 2001, Pages 38-47

  Li, C ^b   Fultz, M E ^b   Geng, W ^b   Ohno, S ^c   Norton, M ^b   Wright, G L ^a,b  

^a MARSHALL UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MARSHALL UNIVERSITY   (United States)

^c Department of Molecular Biology ^*  (Japan)

Author keywords

Cytoskeleton; GFP fusion protein; Microtubules; Protein kinase C; Translocation

Indexed keywords

CYTOCHALASIN B; HYBRID PROTEIN; PHORBOL DIBUTYRATE; PROTEIN KINASE C;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; CELL NUCLEUS; CELLULAR DISTRIBUTION; CONCENTRATION RESPONSE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOSKELETON; EMBRYO; MICROTUBULE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN LOCALIZATION; RAT; SIGNAL TRANSDUCTION;

ANIMALS; AORTA; CELL LINE; CELL MEMBRANE; CELL NUCLEUS; CYTOCHALASIN B; CYTOSKELETON; DOSE-RESPONSE RELATIONSHIP, DRUG; EMBRYO; ENZYME ACTIVATION; FLUORESCEIN-5-ISOTHIOCYANATE; FLUORESCENT DYES; GREEN FLUORESCENT PROTEINS; ISOENZYMES; LUMINESCENT PROTEINS; MICROSCOPY, CONFOCAL; MUSCLE, SMOOTH, VASCULAR; PHORBOL 12,13-DIBUTYRATE; PROTEIN KINASE C; RATS; RECOMBINANT FUSION PROTEINS; TRANSFECTION;

EID: 0035162939     PISSN: 00316768     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004240100627     Document Type: Article

References (49)

1. Purified protein kinase C phosphorylates microtubule-associated protein-2
2. A role for MARKS, the alpha isozyme of protein kinase C, and myosin I in zymosan phagocytosis by macrophages
3. Protein kinase C of smooth muscle
4. Cytoskeletal PKC and ERK/MAPK activation in response to N-nitrosamines and phorbol 12-myristate 13-acetate in gastric adenocarcinoma cells
5. PKCα translocation is microtubule-dependent in passaged smooth muscle cells
6. Intermediate filament reorganization during mitosis is mediated by p34cdc2 phosphorylation of vimentin
7. Integrins and signal transduction pathways: The road taken
8. Intracellular translocation of PKC isoforms in canine pulmonary artery smooth muscle cells by ANG II
9. Protein kinase C - A question of specificity
10. A comparative molecular analysis of four smooth muscle cell lines
11. Protein kinase C translocation in intact vascular smooth muscle strips
12. Endothelial cell tyrosine kinase receptor and G-protein coupled receptor activation involves distinct protein kinase C isoforms
13. Integrin-induced protein kinase C translocation to focal adhesions mediates vascular smooth muscle cell spreading
14. Intracellular targeting and protein kinase C in vascular smooth muscle cells: Specific effects of different membrane-bound receptors
15. Mechanisms of smooth muscle contraction
16. Protein kinase C phosphorylates tau and induces its functional alterations
17. Intermediate filament reconstitution in vitro. The role of phosphorylation in the assembly-disassembly of desmin
18. Association of type 3 protein kinase C with focal contracts in rat embryo fibroblasts
19. 2+ sensitization of myosin light chain phosphorylation in smooth muscle
20. Eyes wide shut: Protein kinase C isozymes are not the only receptors for the phorbol ester tumor promoters
21. Phosphorylation of smooth muscle myosin at two distinct sites by myosin light chain kinase
22. Protein kinase C and the cytoskeleton
23. 2+]; threshold for translocation of the alpha protein kinase C isoform
24. Enzyme translocations during smooth muscle activation
25. Characterization of two putative smooth muscle cell lines from rat thoracic aorta
26. Protein kinase C zeta is associated with the mitotic apparatus in primary cell cultures of the shark rectal gland
27. Protein kinase C regulates alpha v beta 5-dependent cytoskeletal associations and focal adhesion kinase phosphorylation
28. 2+-sensitizing effect of protein kinase C on vascular smooth muscle: Inhibition of myosin light chain phosphatase
29. Distribution of active protein kinase C in smooth muscle
30. Localization of protein kinases by anchoring proteins: A theme in signal transduction
31. Identification of intracellular receptor proteins for activated protein kinase C
32. Tumor promoting phorbol esters induce angiogenesis in vitro
33. Neurofilament expression in human T lymphocytes
34. Protein kinase C associates with intermediate filaments and stress fibers
35. Binding of protein kinase C isoforms to actin in Aplysai
36. Protein Kinase C: Paradigm for regulation of protein function by two membrane-targeting modules
37. Tissue-specific expression of three distinct types of rabbit protein kinase C
38. PKC epsilon-related kinase associates with and phosphorylates cytokeratin 8 and 18
39. Protein kinase C delta associates with vimentin intermediate filaments in differentiated HL60 cells
40. Protein kinase C-independent activation of a novel nonspecific phospholipase C pathway by phorbol myristate acetate releases arachidonic acid for prostaglandin synthesis in MC3T3-EY osteoblasts
41. Protein kinase C in the regulation of smooth muscle contraction
42. Transport of protein kinase C alpha to the nucleus requires intact cytoskeleton while the transport of a protein containing a canonical nuclear localization signal does not
43. Caldesmon, a novel regulatory protein in smooth muscle and nonmuscle actomyosin systems
44. Structure and expression of a smooth muscle cell-specific gene, SM22 alpha
45. Activation of protein kinase C precedes alpha 5 beta 1 integrin-mediated cell spreading on fibronectin
46. Effects of protein kinase Cα overexpression of A7r5 smooth muscle cell proliferation and differentiation
47. Retinol influences contractile function and exerts an anti-proliferative effect on vascular smooth muscle cells through an endothelium-dependent mechanism
48. Differential localization of protein kinase C delta by phorbol esters and related compounds using a fusion protein with green fluorescent protein
49. Bistratene A causes phosphorylation of talin and redistribution of actin microfilaments in fibroblasts: Possible role for PKC-delta