Measurement of serum digitoxin in patients by radioimmunoassay using specific antiserum

Clinica Chimica Acta

Volumn 314, Issue 1-2, 2001, Pages 245-247

  Ikeda, Yukari ^a   Fujii, Masahiro ^a   Yamazaki, Mikio ^b   Fujii, Youichi ^a  

^a HOKURIKU UNIVERSITY   (Japan)

^b Kinjyo Hospital   (Japan)

Author keywords

Anti digitoxin antiserum; Digitoxin; Digitoxin 3 hemisuccinate BSA conjugate; RIA

Indexed keywords

ANTISERUM; BOVINE SERUM ALBUMIN; DIGITOXIN; DIGITOXIN 3' HEMISUCCINATE; DIGITOXIN ANTISERUM; UNCLASSIFIED DRUG; ANTIBODY; CARDIOTONIC AGENT; DIGITOXIGENIN;

ANTIBODY SPECIFICITY; ARTICLE; CONTROLLED STUDY; CROSS REACTION; DIGITALIZATION; DRUG DETERMINATION; DRUG METABOLISM; HUMAN; PRIORITY JOURNAL; RADIOIMMUNOASSAY; SERUM; ANIMAL; BLOOD; CHEMISTRY; CONGESTIVE HEART FAILURE; IMMUNOLOGY; RABBIT; REPRODUCIBILITY;

ANIMAL; ANTIBODIES; ANTIBODY SPECIFICITY; CARDIOTONIC AGENTS; CROSS REACTIONS; DIGITOXIGENIN; DIGITOXIN; HEART FAILURE, CONGESTIVE; HUMAN; RABBITS; RADIOIMMUNOASSAY; REPRODUCIBILITY OF RESULTS; SERUM ALBUMIN, BOVINE;

EID: 0035162222     PISSN: 00098981     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-8981(01)00635-0     Document Type: Article

References (14)

1. Digoxin-specific antibodies
2. The measurement of digitoxin in human serum by radioimmunoassay
3. The reactivity of derivatives of digoxin and digitoxin as measured by the Na-K-ATPase displacement assay and by radioimmunoassay
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5. Preparation of specific antiserum to digitoxin by using digitoxin hemisuccinate-bovine serum albumin conjugate at the digitoxose C-3′ position
6. Preparation and antigenic properties of digitoxin-bovine serum albumin conjugates linked at the digitoxose C-3′ and C-3″ positions
7. Quantitation of digitoxin and the bis- and monodigitoxosides of digitoxigenin in serum
8. Simultaneous analysis of digitoxin and its clinically relevant metabolites using high-performance liquid chromatography and radioimmunoassay
9. Enhanced transformation of digitoxin to dihydrodigitoxin in humans with renal failure
10. Interference of oleandrin and oleandrigenin in digitoxin immunoassays: Minimal cross reactivity with a new monoclonal chemiluminescent assay and high cross reactivity with the fluorescence polarization assay
11. Convergence of three methods to resolve discrepant immunoassay digitoxin results
12. Improved receptor assay for measuring digoxin activity
13. Specificity of digoxin immunoassays toward digoxin metabolites
14. Digoxin immunoassay with cross-reactivity of digoxin metabolites proportional to their biological activity