An isoform-specific interaction of the membrane anchors affects mammalian adenylyl cyclase type V activity

European Journal of Biochemistry

Volumn 268, Issue 1, 2001, Pages 105-110

  Seebacher, Thomas ^a   Linder, Jürgen U ^a   Schultz, Joachim E ^a,b  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b Pharmazeutisches Institut   (Germany)

Author keywords

Adenylyl cyclase; CAMP; Forskolin; G protein; Membrane anchor

Indexed keywords

ADENYLATE CYCLASE; CYCLIC AMP; FORSKOLIN; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); MEMBRANE ENZYME;

ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME LOCALIZATION; ENZYME MECHANISM; ENZYME POLYMORPHISM; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION;

ADENYLATE CYCLASE; ANIMALS; BLOTTING, WESTERN; CATTLE; CELLS, CULTURED; FORSKOLIN; GTP-BINDING PROTEINS; HUMANS; ISOENZYMES; RABBITS; RECOMBINANT PROTEINS;

MAMMALIA;

EID: 0035161911     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.2001.01850.x     Document Type: Article

References (29)

1. Adenylyl cyclases: Structure, regulation and function in an enzyme superfamily
2. Molecular diversity of the adenylyl cyclases
3. Complexity and diversity of mammalian adenylyl cyclases
4. sα and forskolin
5. Interactions of forskolin and ATP with the cytosolic domains of mammalian adenylyl cyclase
6. Identification of functional domains of adenylyl cyclase using in vivo chimeras
7. Molecular cloning and expression of a novel type V adenylyl cyclase from rabbit myocardium
8. Cloning and expression of a bovine adenylyl cyclase type VII specific to the retinal pigment epithelium
9. Site-directed mutagenesis of virtually any plasmid by eliminating a unique site
10. Calcium phosphate transfection
11. A highly sensitive adenylate cyclase assay
12. A functional chimera of mammalian guanylyl and adenylyl cyclases
13. Adenylyl cyclase amino acid sequence: Possible channel- or transporter-like structure
14. sα with the cytosolic domains of mammalian adenylyl cyclase
15. Differential effects of ceramides upon adenylyl cyclase subtypes
16. Regulation of adenylyl cyclase by membrane potential
17. 2+-inhibitable adenylyl cyclase in non-excitable cells
18. 2+ entry
19. Identification and subcellular localization of the subunits of L-type calcium channels and adenylyl cyclase in cardiac myocytes
20. Neurobiology. Receptors as kissing cousins
21. Receptors for dopamine and somatostatin: Formation of hetero-oligomers with enhanced functional activity
22. Regulation of type V adenylyl cyclase by PMA-sensitive and insenstive protein kinase C isoenzymes in intact cells
23. Isolation and characterization of constitutively active mutants of mammalian adenylyl cyclase
24. sα
25. Activating mutation of adenylyl cyclase reverses its inhibition by G proteins
26. Characterization of soluble forms of nonchimeric type V adenylyl cyclases
27. iα subunits of heterotrimeric G proteins
28. sα