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Volumn 76, Issue 1, 2001, Pages 182-190

Tubulin stimulates adenylyl cyclase activity in C6 glioma cells by bypassing the β-adrenergic receptor: A potential mechanism of G protein activation

Author keywords

Adenylyl cyclase; Cyclic AMP; Cytoskeleton; Microtubules; Signal transduction

Indexed keywords

ADENYLATE CYCLASE; BETA ADRENERGIC RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE TRIPHOSPHATE; GUANOSINE TRIPHOSPHATE DERIVATIVE; GUANYLYLIMIDODIPHOSPHATE; ISOPRENALINE; NUCLEOTIDE; SAPONIN; TUBULIN;

EID: 0035158389     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2001.00013.x     Document Type: Article
Times cited : (26)

References (46)
  • 1
    • 0027526590 scopus 로고
    • Enhancement of β-adrenergic responses by Gi-linked receptors in rat hippocampus
    • (1993) Neuron , vol.10 , pp. 83-88
    • Andrade, R.1
  • 11
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • (1970) Nature , vol.227 , pp. 680-689
    • LaemmLi, U.K.1
  • 12
    • 0026474549 scopus 로고
    • Activation of the α subunits of Gs in intact cells alter its abundance, rate of degradation, and membrane avidity
    • (1992) J. Cell Biol. , vol.119 , pp. 1297-1307
    • Levis, M.J.1    Bourne, H.R.2
  • 14
    • 0033574522 scopus 로고    scopus 로고
    • Interaction of heterotrimeric G protein Gaq with Purkinje cell protein-2. Evidence for a novel nucleotide exchange factor
    • (1999) J. Biol. Chem. , vol.274 , pp. 10685-10688
    • Luo, Y.1    Denker, B.M.2
  • 16
    • 0027936892 scopus 로고
    • Membrane organization in G-protein mechanisms
    • (1994) FASEB J. , vol.8 , pp. 939-946
    • Neubig, R.R.1
  • 20
  • 24
    • 0023884769 scopus 로고
    • Exchange of guanine nucleotides between tubulin and GTP-binding proteins that regulate adenylate cyclase: Cytoskeletal modification of neuronal signal transduction
    • (1988) J. Neurochem. , vol.51 , pp. 300-311
    • Rasenick, M.M.1    Wang, N.2
  • 31
    • 0027934665 scopus 로고
    • Tubulin-G protein association stabilizes GTP binding and activates GTPase: Cytoskeletal participation in neuronal signal transduction
    • (1994) Biochemistry , vol.33 , pp. 9800-9805
    • Roychowdhury, S.1    Rasenick, M.M.2
  • 32
    • 0027235428 scopus 로고
    • G protein binding and G protein activation by nucleotide transfer involve distinct domains on tubulin: Regulation of signal transduction by cytoskeletal elements
    • (1993) Biochemistry , vol.32 , pp. 4955-4961
    • Roychowdhury, S.1    Wang, N.2    Rasenick, M.M.3
  • 34
    • 0026520463 scopus 로고
    • Extracellular ATP stimulates three different receptor-signal transduction systems in FRTL-5 thyroid cells. Activation of phospholipase C, and inhibition and activation of adenylate cyclase
    • (1992) Biochem. J. , vol.283 , pp. 281-287
    • Sato, K.1    Okajima, F.2    Kondo, Y.3
  • 45
    • 0006575919 scopus 로고
    • Cytoskeletal participation in the signal transduction process: Tubulin G protein interactions in the regulation of adenylate cyclase
    • Biology of Cellular Transducing Signals (Vanderhoek J.Y. ed). Plenum Press. New York
    • (1990) , pp. 163-172
    • Yan, K.1    Rasenick, M.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.