Influence of wet granulation and lubrication on the powder and tableting properties of codried product of microcrystalline cellulose with β-cyclodextrin

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 51, Issue 1, 2001, Pages 63-69

  Wu, J S ^a   Ho, H O ^a   Sheu, M T ^a  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Lubrication; Microcrystalline cellulose; Wet granulation

Indexed keywords

AVICEL PH 301; BETA CYCLODEXTRIN; MAGNESIUM STEARATE; MICROCRYSTALLINE CELLULOSE; UNCLASSIFIED DRUG;

ARTICLE; BULK DENSITY; CRUSHING STRENGTH; DRUG GRANULATION; LUBRICATION; PARTICLE SIZE; POWDER; TABLET COMPRESSION; WATER CONTENT;

ANALYSIS OF VARIANCE; BETA-CYCLODEXTRINS; CELLULOSE; CYCLODEXTRINS; LUBRICATION; POWDERS; STEARIC ACIDS; TABLETS;

EID: 0035158060     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0939-6411(00)00137-5     Document Type: Article

References (10)

1. Bonding surface area and bonding mechanism-two important factors for the understanding of powder compactability
2. Effect of addition of water on the rheological and mechanical properties of microcrystalline celluloses
3. The changes in the mechanic properties of a direct tableting agent microcrystalline cellulose by precompression
4. The influence of particle size and shape on the angle of internal friction and the flow factor of unlubricated and lubricated powders
5. Comparative compaction properties of various microcrystalline cellulose types and generic products
6. Direct compression vehicles. Evaluation of some common diluents
7. Modification of physical characteristics of microcrystalline cellulose by codrying with β-cyclodextrins
8. The effect of moisture on the mechanical and powder flow properties of microcrystalline cellulose
9. Studies on direct compression of tablets XVI. the use of surface area measurements for the evaluation of bonding surface area in compressed powders
10. Overview of compaction data analysis techniques