Antigens to viral capsid and non-capsid proteins are present in brain tissues and antibodies in sera of Theiler's virus-infected mice

Journal of Virological Methods

Volumn 91, Issue 1, 2001, Pages 11-19

  Cameron, K ^a   Zhang, X ^a   Seal, B ^a   Rodriguez, M ^a   Njenga, M K ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Antibody; Encephalitis; Recombinant proteins; Theiler's murine encephalomyelitis virus

Indexed keywords

CAPSID PROTEIN; EPITOPE; NEUTRALIZING ANTIBODY; PROTEIN PRECURSOR; RECOMBINANT PROTEIN; VIRUS ANTIBODY; VIRUS ANTIGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY RESPONSE; ARTICLE; ASTROCYTE; BRAIN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOPATHOLOGY; MOUSE; MURINE ENCEPHALOMYELITIS VIRUS; NONHUMAN; PRIORITY JOURNAL; RABBIT; VIRUS CAPSID; VIRUS INFECTION; VIRUS PARTICLE; VIRUS RECOMBINANT; VIRUS REPLICATION;

ANIMALS; ANTIBODIES, VIRAL; ASTROCYTES; BLOTTING, WESTERN; BRAIN; CAPSID; CARDIOVIRUS INFECTIONS; CELL LINE; CROSS REACTIONS; MICE; MICE, INBRED C57BL; RABBITS; RECOMBINANT PROTEINS; THEILOVIRUS; VIRAL PROTEINS;

EID: 0035155961     PISSN: 01660934     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-0934(00)00246-9     Document Type: Article

References (27)

1. b molecules complexed with a viral VP2 peptide lacking a consensus anchor residue
2. Effect of immunization with Theiler's virus on the course of demyelinating disease
3. Theiler's virus and Mengo virus induce cross-reactive cytotoxic T lymphocytes restricted to the same immunodominant VP2 epitope in C57BL/6 mice
4. Immortalization of immature and mature mouse astrocytes with SV40 T antigen
5. Stepwise transformation of astrocytes by simian virus 40 large T antigen and epidermal growth factor receptor overexpression
6. Analysis of antibody responses to predominant linear epitopes on Theiler's murine encephalomyelitis virus
7. 121-130 in the absence of endogenous CD4 help, tumor necrosis factor-α, γ-interferon, perforin, or costimulation through CD28
8. Inhibition of Theiler's virus-mediated demyelintation by peripheral immune tolerance induction
9. Immune mechanisms of Theiler's virus induced demyelination
10. Identification and localization of a limited number of predominant conformation-independent antibody epitopes of Theiler's murine encephalomyelitis virus
11. Theiler's virus infection in mice: An unusual biphasic disease process leading to demyelination
12. Neutralizing monoclonal antibodies to Theiler's murine encephalomyelitis viruses
13. Localization of a neutralization site of Theiler's murine encephalomyelitis viruses
14. Absence of spontaneous central nervous system remyelination in class II-deficient mice infected with Theiler's virus
15. Theiler's virus persistence and demyelination in major histocompatibility complex class II-deficient mice
16. Molecular cloning and sequence determination of DA strain of Theiler's murine encephalomyelitis viruses
17. Picornavirus nonstructural proteins: Emerging roles in virus replication and inhibition of host functions
18. Successful therapy of Theiler's virus-induced demyelination (DA strain) with monoclonal anti-Lyt 2 antibody
19. Persistent infection of oligodendrocytes in Theiler's virus-induced encephalomyelitis
20. Theiler's murine encephalomyelitis virus: A model of demyelination and persistence of virus
21. The balance between persistent infection and immune cells determines demyelination
22. DNA sequencing with chain-terminating inhibitors
23. Fluorescence detection in automated DNA sequence analysis
24. Major linear antibody epitopes and capsid proteins differentially induce protective immunity against Theiler's virus-induced demyelinating disease
25. 233-244
26. Identification of a major T-cell epitope within VP3 amino acid residues 24 to 37 of Theiler's virus in demyelination-susceptible SJL/J mice
27. Role of individual T cell epitopes of Theiler's virus in pathogenesis of demyelination correlates with the ability to induce a Th1 response