Oxidation of LDL enhances the cholesteryl ester transfer protein (CETP)-mediated cholesteryl ester transfer rate to HDL, bringing on a diminished net transfer of cholesteryl ester from HDL to oxidized LDL

Clinica Chimica Acta

Volumn 304, Issue 1-2, 2001, Pages 99-106

  Castilho, Lucia N ^a   Oliveira, Helena C F ^a   Cazita, Patrícia M ^b   De Oliveira, Admar C ^a   Sesso, Antonio ^b   Quintão, Eder C R ^b  

^a UNIVERSITY OF CAMPINAS   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Acetylated LDL; Cholesteryl ester transfer protein; HDL; Oxidized LDL; Reverse cholesterol transport

Indexed keywords

ACETYL LOW DENSITY LIPOPROTEIN; APOLIPOPROTEIN B; CARBON 14; CHOLESTEROL ESTER; CHOLESTEROL ESTER TRANSFER PROTEIN; HIGH DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; OXIDIZED LOW DENSITY LIPOPROTEIN; TRITIUM;

ARTICLE; ATHEROGENESIS; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; HUMAN; LIPID COMPOSITION; LIPID OXIDATION; LIPOPROTEIN METABOLISM; PRIORITY JOURNAL; REACTION ANALYSIS; TRANSPORT KINETICS;

CARRIER PROTEINS; CHOLESTEROL ESTER TRANSFER PROTEINS; CHOLESTEROL ESTERS; GLYCOPROTEINS; HUMANS; KINETICS; LIPOPROTEINS, HDL; LIPOPROTEINS, LDL; OXIDATION-REDUCTION;

EID: 0035155870     PISSN: 00098981     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-8981(00)00401-0     Document Type: Article

References (47)

1. Plasma lipid transfer proteins, high density lipoproteins and reverse cholesterol transport
2. A receptor mediated pathway for cholesterol homeostasis
3. Plasma lipid transfer protein
4. Is reverse cholesterol transport a misnomer for suggesting its role in the prevention of atheroma formation?
5. Severe atherosclerosis in transgenic mice expressing simian cholesteryl ester transfer protein
6. Increased atherosclerosis in apoE and LDL receptor gene knock-out mice as a result of human cholesteryl ester transfer protein transgene expression
7. Increased coronary heart disease in Japanese-American men with mutation in the cholesteryl ester transfer protein gene
8. Genetic cholesteryl ester transfer protein deficiency is extremely frequent in the Omagari area of Japan. Marked hyperalphalipoproteinemia caused by CETP gene mutation is not associated with longevity
9. A low prevalence of coronary heart disease among subjects with increased high density lipoprotein cholesterol levels, including those with plasma cholesteryl ester transfer protein deficiency
10. The role of a common variant of the cholesteryl ester transfer protein gene in the progression of coronary atherosclerosis
11. Cloning and sequencing of human cholesteryl ester transfer protein c-DNA
12. Dietary cholesterol increases transcription of human cholesteryl ester transfer protein gene in transgenic mice: Dependence of natural flanking sequences
13. Human cholesteryl ester transfer protein gene proximal promoter contains dietary cholesterol positive response elements and mediates expression in small intestine and periphery while predominant liver and spleen expression is controlled by 5′-distal sequences. Cis-acting sequences mapped in transgenic mice
14. Relation of adipose tissue cholesteryl ester transfer protein (CETP) mRNA to plasma concentrations of CETP in man
15. Mammalian adipose tissue and muscle are major sources of lipid transfer protein mRNA
16. Beyond cholesterol modifications of low density lipoprotein that increase atherogenicity
17. Lesioned low density lipoprotein in atherosclerotic apolipoprotein E-deficient transgenic mice and in humans is oxidized and aggregated
18. Lipoprotein oxidation and progression of carotid atherosclerosis
19. Presence of a modified low density lipoprotein in humans
20. -)
21. Increase in thiobarbituric acid-reactive substances and vascular complications in type 2 diabetes mellitus
22. Hyperlipidemia of chronic renal failure
23. Lipid peroxidation of circulating low density lipoproteins with age, smoking and in peripheral vascular disease
24. Dense low lipoprotein subspecies with diminished oxidative resistance predominate in combined hyperlipidemia
25. LDL physical and chemical properties in familial combined hyperlipidemia
26. Exchange of oxidized cholesteryl linoleate between LDL and HDL mediated by cholesteryl ester transfer protein
27. 2+-mediated oxidation of dialyzed plasma: Effects on low and high density lipoproteins and cholesteryl ester transfer protein
28. Evidence for electronegativity of plasma high density lipoprotein 3 as one major determinant of human cholesteryl ester transfer protein activity
29. Cholesterol ester transfer mediated by lipid transfer protein as influenced by changes in the charge characteristics of plasma lipoproteins
30. Purification, microheterogeneity, and stability of human lipid transfer protein
31. The distribution and chemical composition of ultracentrifugally separated lipoprotein in human serum
32. In vitro incorporation of radiolabeled cholesteryl esters into high and low density lipoproteins
33. Degradation of cationized low density lipoprotein and regulation of cholesterol metabolism in homozygous hypercholesterolemia fibroblasts
34. Iron and copper promote modification of low density lipoprotein by human arterial smooth muscle cells in culture
35. Methods to determine oxidation of low density lipoprotein
36. 1 in the rat: Effects of lipid transfer protein
37. Protein measurement with Folin phenol reagent
38. Phosphorus assay in column chromatography
39. Application of electron microscopy to the study of plasma lipoproteins structure
40. High density lipoprotein is the major carrier of lipid hydroperoxides in human blood plasma from fasting donors
41. Complete cholesteryl ester transfer protein deficiency increases oxidized-LDL in plasma
42. Lipoprotein desialylation simultaneously enhances the cell cholesterol uptake and impairs the reverse cholesterol transport system: In vitro evidences utilizing neuraminidase-treated lipoproteins and mouse peritoneal macrophages
43. Plasma lipoproteins from patients with poorly controlled diabetes mellitus and "in vitro" glycation of lipoproteins enhance the transfer rate of cholesteryl ester from HDL to apo-B-containing lipoproteins
44. Oxidation-labile subfraction of human plasma low density lipoprotein isolated by ion-exchange chromatography
45. 2 activity in endothelial cell-induced modification of low density lipoprotein
46. Role of superoxide in endothelial-cell modification of low density lipoproteins
47. Purification and characterization of a human plasma cholesteryl ester transfer protein