The transport of a reversible proton pump antagonist, 5,6-dimethyl-2-(4-fluorophenylamino)-4-(1-methyl-1,2,3,4-tetrahydroisoquinoli ne-2-yl) pyrimidine hydrochloride (YH1885), across Caco-2 cell monolayers

Drug Metabolism and Disposition

Volumn 29, Issue 1, 2001, Pages 54-59

  Li, Hong ^a   Chung, Suk Jae ^a   Kim, Dong Chool ^b   Kim, Hyun Soo ^c   Lee, Jong Wook ^c   Shim, Chang Koo ^a  

^a Seoul National University   (South Korea)

^b Chungnam National University   (South Korea)

^c Yuhan Corporation   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

2 [(4 HYDROXYPHENYL)AMINO] 4 (1,2,3,4 TETRAHYDROISOQUINOLINE 2 YL)QUINAZOLINE; 2 METHYL 4 (4,5,6,7 TETRAHYDROTHIENO[3,2 C]PYRIDINE 5 YL)QUINAZOLINE; 2 METHYL 4 [(THIOPHEN 2 YL)METHYLAMINO]QUINAZOLINE; 5,6 DIMETHYL 2 (4 FLUOROPHENYLAMINO) 4 (1 METHYL 1,2,3,4 TETRAHYDROISOQUINOLINE 2 YL)PYRIMIDINE; 8 METHOXY 4 (2 METHOXYPHENYLMETHYL N METHYLAMINO) 2 METHYLQUINAZOLINE; DIPYRIDAMOLE; ISOQUINOLINE DERIVATIVE; NUCLEIC ACID BASE; PAPAVERINE; PHLORIZIN; PROTON PUMP INHIBITOR; PYRIMIDINE DERIVATIVE; REVAPRAZAN; THYMINE; UNCLASSIFIED DRUG; URACIL DERIVATIVE; YH 1013; YH 1041; YH 1070; YH 957;

APICAL MEMBRANE; ARTICLE; BASOLATERAL MEMBRANE; CELL STRAIN CACO 2; CONCENTRATION RESPONSE; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG SOLUBILITY; DRUG STRUCTURE; DRUG TRANSPORT; DRUG UPTAKE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; STRUCTURE ANALYSIS;

BIOLOGICAL TRANSPORT; CACO-2 CELLS; EPITHELIAL CELLS; HUMANS; ISOQUINOLINES; PROTON PUMPS; PYRIMIDINONES; SODIUM; TETRAHYDROISOQUINOLINES;

EID: 0035153379     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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