Directed neutrophil migration to IL-8 is increased in cystic fibrosis: A study of the effect of erythromycin

Thorax

Volumn 56, Issue 1, 2001, Pages 62-64

  Brennan, S ^a   Cooper, D ^b   Sly, P D ^a,b  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

Cystic fibrosis; Erythromycin; Neutrophils

Indexed keywords

ERYTHROMYCIN; FORMYLMETHIONYLLEUCYLPHENYLALANINE; INTERLEUKIN 8;

ARTICLE; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; CYSTIC FIBROSIS; DISEASE ASSOCIATION; DRUG ACTIVITY; FEMALE; HUMAN; HUMAN CELL; INFLAMMATION; LEUKOCYTE MIGRATION; MALE; NEUTROPHIL CHEMOTAXIS; PRIORITY JOURNAL;

ADOLESCENT; ANTI-BACTERIAL AGENTS; CHEMOTAXIS, LEUKOCYTE; CHILD; CYSTIC FIBROSIS; ERYTHROMYCIN; FEMALE; HUMANS; INTERLEUKIN-8; MALE; N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE; NEUTROPHILS;

EID: 0035152203     PISSN: 00406376     EISSN: None     Source Type: Journal    
DOI: 10.1136/thorax.56.1.62     Document Type: Article

References (11)

1. Elastin and collagen degradation products in urine of patients with cystic fibrosis
2. Diffuse panbronchiolitis and cystic fibrosis: East meets West
3. Long-term low-dose administration of erythromycin to patients with diffuse panbronchiolitis
4. Erythromycin reduces neutrophils and neutrophil-derived elastolytic-like activity in the lower respiratory tract of bronchiolitis patients
5. Receptors and intracellular signaling in human neutrophils
6. Distinct sputum cytokine profiles in cystic fibrosis and other chronic inflammatory airway disease
7. Desensitisation of neutrophil responses by systemic interleukin-8 in cystic fibrosis
8. Decreased polymorphonuclear leucocyte chemotactic response to leukotriene B4 in cystic fibrosis
9. Increased cytosolic calcium in cystic fibrosis neutrophils: Effect on stimulus-secretion coupling
10. Neutrophil chemotaxis in acutely infected and clinically stable cystic fibrosis patients
11. Modulation of human polymorphonuclear neutrophil function by macrolides: Preliminary data concerning dirithromycin