Differences in the uptake and nuclear localization of anti-proliferative heparan sulfate between human lung fibroblasts and human lung carcinoma cells

Journal of Cellular Biochemistry

Volumn 83, Issue 4, 2001, Pages 597-606

  Cheng, Fang ^a   Petersson, Per ^a   Arroyo Yanguas, Yolanda ^a   Westergren Thorsson, Gunilla ^a  

^a LUND UNIVERSITY   (Sweden)

Author keywords

Antiproliferative activity; Confocal microscopy; Heparan sulfate; Nuclear localization

Indexed keywords

HEPARAN SULFATE; IDURONIC ACID; IODINE 125; RHODAMINE;

ARTICLE; BINDING SITE; CELL NUCLEUS; CELLULAR DISTRIBUTION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; LUNG CARCINOMA; LUNG FIBROBLAST; PRIORITY JOURNAL;

ANIMALS; BINDING SITES; CATTLE; CELL NUCLEUS; CELL TRANSFORMATION, NEOPLASTIC; CELLS, CULTURED; FIBROBLASTS; GROWTH INHIBITORS; HEPARITIN SULFATE; HUMANS; LUNG; LUNG NEOPLASMS; MICROSCOPY, CONFOCAL; RADIOLIGAND ASSAY; TUMOR CELLS, CULTURED;

EID: 0035149728     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcb.1254     Document Type: Article

References (46)

1. Binding, internalization, and degradation of antiproliferative heparan sulphate by human embryonic lung fibroblasts
2. Entry and distribution of fluorescent antiproliferative heparin derivatives into rat vascular smooth muscle cells. Comparison between heparin-sensitive and heparin-resistant cultures
3. Proteoglycan involvement in polyamine uptake
4. Functions of cell surface heparan sulfate proteoglycans
5. Trans-repressor activity of nuclear glycosaminoglycans on Fos and Jun/Ap1 oncoprotien-mediated transcription
6. Binding and internalization of heparin by vascular smooth muscle cells
7. A new method for sequence analysis of glycosaminoglycans from heavily substituted proteoglycans reveals non-random positioning of 4- and 6-O-sulphated N-acetylgalactosamine in aggrecan-derived chondroitin sulphate
8. Patterns of uronosyl epimerization and 4-/6-O-sulphation in chondroitin/dermatan sulphate from decorin and biglycan of various bovine tissues
9. Structural characteristics of heparan sulfates with varying sulfate contents
10. Proteoglycans on normal and migrating human corneal endothelium
11. Effect of heparin and liver heparan sulphate on interaction of HepG2-derived transcription factors and their cis-acting elements: Altered potential of hepatocellular carcinoma heparan sulphate
12. Binding of human syndecan to extracellular matrix proteins
13. A unique heparan sulphate in the nuclei of hepatocytes: Structural changes with the growth state of the cells
14. Interactions between dermatan sulfate chains. Light-scattering and viscometry studies of self-association
15. Interaction between heparan sulphate chains. A gel chromatographic, light-scattering and structural study of aggregating and non-aggregating chains
16. Structural studies on heparan sulphates. Characterization of oligosaccharides; obtained by periodate oxidation and alkaline elimination
17. Heparan sulphate in the binding and activation of basic fibroblast growth factor
18. Structure and function of heparan sulphate proteoglycans
19. Determination of cell number in monolayer cultures
20. Basic fibroblast growth factor (FGF-2) internalization through the heparan sulafte proteoglycans-mediated pathway: An ultrastructural approach
21. Binding of heparin and of the small proteoglycan decorin to the same endocytosis receptor proteins leads to different metabolic consequences
22. Protein kinase C alpha expression is required for heparin inhibition of rat smooth muscle cell proliferation in vitro and in vivo
23. Nuclear localization of glycosaminoglycans in rat ovarian granulosa cells
24. Matrix proteoglycans: From molecular design to cellular function
25. Ligand affinity cloning and structure of a cell surface heparan sulfate proteoglycan that binds basic fibroblast growth factor
26. Proteoglycans: Structure and interactions
27. Glypican and biglycan in the nuclei of neurons and glioma cells: Presence of functional nuclear localization signals and dynamic changes in glypican during the cell cycle
28. Structural studies of heparan sulfates
29. Heparan sulfate proteoglycans as adhesive and antinvasive molecules. Syndecans and glypican have distinct functions
30. Heparan sulfate proteoglycans as adhesive and anti-invasive molecules. Syndecans and glypican have distinct functions
31. Heparan sulfate upregulates platelet-derived growth factor receptors on human lung fibroblasts
32. Heparin inhibits mitogen-activated protien kinase-dependent and - Independent c-fos induction of mesangial cells
33. Heparin inhibits mitogen activated protein kinase activation in intact rat vascular smooth muscle cells
34. Heparin inhibits c-fos and c-myc mRNA expression in vascular smooth muscle cells
35. Binding and internalization of exogenous glycosaminoglycans in weakly and highly meastatic rhabdomyosarcoma cells
36. Heparan sulfate: A piece of information
37. Growth factors in the extracellular matrix
38. Molecular cloning and expression of the acidic fibroblast growth factor receptors in a rat parathyroid cell line (PT-r). Parathyroid cell- specific calcium-dependent change of ligand accessibility and covalent attachment of heparan sulfate glycosaminoglycan to the receptors
39. Protein kinase C activates the MEK-ERK pathway in a manner independent of Ras and dependent on Raf
40. Binding, internalization and degradation of heparin and heparin fragments by cultured endothelial cells
41. Proliferation of cultured fibroblasts is inhibited by L-iduronate-containing glycosaminoglycans
42. L-Iduronate-rich glycosaminoglycans inhibit growth of normal fibroblasts independently of serum or added growth factors
43. Syndecans: Synergistic activators of cell adhesion
44. Heparin suppresses the induction of c-fos and c-myc mRNA in murine fibroblasts by selective inhibition of a protein kinase C-dependent pathway
45. Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor